Targeting mTOR as a Therapeutic Approach in Medulloblastoma

Targeting mTOR as a Therapeutic Approach in Medulloblastoma

Mechanistic target of rapamycin (mTOR) is a master signaling pathway that regulates organismal growth and homeostasis, because of its implication in protein and lipid synthesis, and in the control of the cell cycle and the cellular metabolism. Moreover, it is necessary in cerebellar development and...

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Bibliographic Details
Main Authors: Juncal Aldaregia, Ainitze Odriozola, Ander Matheu, Idoia Garcia
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:International Journal of Molecular Sciences
Subjects:
mTOR
Medulloblastoma
MBSCs
Online Access:http://www.mdpi.com/1422-0067/19/7/1838

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