(1R,3S,5R,6S)-6-Hydroxy-3-tosyloxytropan-8-ium chloride
The title compound, C15H22NO4S+·Cl−, is a hydrolysis product of lesatropane [(1R,3S,5R,6S)-6-acetoxy-3-tosyloxytropane] hydrochloride, a potential antiglaucoma agent. As in lesatropane, the piperidine and pyrrolidine rings in the title compound adopt chair and envelope con...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
International Union of Crystallography
2010-02-01
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| Series: | Acta Crystallographica Section E |
| Online Access: | http://scripts.iucr.org/cgi-bin/paper?S1600536809055366 |
| Summary: | The title compound, C15H22NO4S+·Cl−, is a hydrolysis product of lesatropane [(1R,3S,5R,6S)-6-acetoxy-3-tosyloxytropane] hydrochloride, a potential antiglaucoma agent. As in lesatropane, the piperidine and pyrrolidine rings in the title compound adopt chair and envelope conformations, respectively. There are two molecules in the unit cell with similar conformations. The crystal structure is stabilized by intermolecular O—H...Cl and N—H...Cl hydrogen bonds. |
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| ISSN: | 1600-5368 |