Telomere Transcripts Target Telomerase in Human Cancer Cells
Long non-coding transcripts from telomeres, called telomeric repeat-containing RNA (TERRA), were identified as blocking telomerase activity (TA), a telomere maintenance mechanism (TMM), in tumors. We expressed recombinant TERRA transcripts in tumor cell lines with TA and with alternative lengthening...
Main Authors: | Theresa Kreilmeier, Doris Mejri, Marlene Hauck, Miriam Kleiter, Klaus Holzmann |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2016-08-01
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Series: | Genes |
Subjects: | |
Online Access: | http://www.mdpi.com/2073-4425/7/8/46 |
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