Hemorrhage Caused by Snake Venom Metalloproteinases: A Journey of Discovery and Understanding

Hemorrhage Caused by Snake Venom Metalloproteinases: A Journey of Discovery and Understanding

The historical development of discoveries and conceptual frames for understanding the hemorrhagic activity induced by viperid snake venoms and by hemorrhagic metalloproteinases (SVMPs) present in these venoms is reviewed. Histological and ultrastructural tools allowed the identification of the capil...

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Bibliographic Details
Main Authors: José María Gutiérrez, Teresa Escalante, Alexandra Rucavado, Cristina Herrera
Format: Article
Language:English
Published: MDPI AG 2016-03-01
Series:Toxins
Subjects:
snake venom
viperids
metalloproteinases
hemorrhage
capillary vessels
basement membrane
type IV collagen
Online Access:http://www.mdpi.com/2072-6651/8/4/93

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