CSF Neurofilament Light Chain Elevation Predicts ALS Severity and Progression

CSF Neurofilament Light Chain Elevation Predicts ALS Severity and Progression

Objectives: This study compared neurofilament light chain (NFL) levels in the cerebrospinal fluid (CSF) of patients with sporadic amyotrophic lateral sclerosis (sALS) with levels in patients with other neurological diseases and healthy controls and assessed correlations between NFL levels and clinic...

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Bibliographic Details
Main Authors: Qionghua Sun, Xue Zhao, Siyuan Li, Fei Yang, Hongfen Wang, Fang Cui, Xusheng Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Neurology
Subjects:
amyotrophic lateral sclerosis
neurofilament light chain
NFL
CSF
axonal damage
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2020.00919/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2020.00919/full

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