Rationale for COVID-19 Treatment by Nebulized Interferon-β-1b–Literature Review and Personal Preliminary Experience

Rationale for COVID-19 Treatment by Nebulized Interferon-β-1b–Literature Review and Personal Preliminary Experience

The inflammatory response to COVID-19 is specifically associated with an impaired type I interferon (IFN) response and complete blockade of IFN-β secretion. Clinically, nebulization of IFN-α-2b has been historically used in China to treat viral pneumonia associated with SARS-CoV. Very recent data sh...

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Bibliographic Details
Main Authors: Aurélien Mary, Lucie Hénaut, Pierre Yves Macq, Louise Badoux, Arnaud Cappe, Thierry Porée, Myriam Eckes, Hervé Dupont, Michel Brazier
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Pharmacology
Subjects:
COVID-19
SARS-CoV-2
nebulization
inflammation
interferon-β-1b
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.592543/full

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