Comparative palatability of orally disintegrating tablets (ODTs) of Praziquantel (L-PZQ and Rac-PZQ) versus current PZQ tablet in African children: A randomized, single-blind, crossover study.
<h4>Background</h4>Praziquantel (PZQ) is currently the only recommended drug for infection and disease caused by the schistosome species that infects humans; however, the current tablet formulation is not suitable for pre-school age children mainly due to its bitterness and the large tab...
Main Authors: | Muhidin K Mahende, Eric Huber, Elly Kourany-Lefoll, Ali Ali, Brooke Hayward, Deon Bezuidenhout, Wilhelmina Bagchus, Abdunoor M Kabanywanyi |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2021-06-01
|
Series: | PLoS Neglected Tropical Diseases |
Online Access: | https://doi.org/10.1371/journal.pntd.0007370 |
Similar Items
-
Expanding Praziquantel (PZQ) Access beyond Mass Drug Administration Programs: Paving a Way Forward for a Pediatric PZQ Formulation for Schistosomiasis.
by: Amaya L Bustinduy, et al.
Published: (2016-09-01) -
Morphological Characteristics of Schistosoma mansoni PZQ-resistant and -susceptible Strains are Different in Presence of Praziquantel
by: António ePinto-Almeida, et al.
Published: (2016-04-01) -
Relative Bioavailability of Orally Dispersible Tablet Formulations of Levo‐ and Racemic Praziquantel: Two Phase I Studies
by: Wilhelmina Maria Bagchus, et al.
Published: (2019-01-01) -
Pharmacokinetic Study of Praziquantel Enantiomers and Its Main Metabolite R-trans-4-OH-PZQ in Plasma, Blood and Dried Blood Spots in Opisthorchis viverrini-Infected Patients.
by: Isabel Meister, et al.
Published: (2016-05-01) -
Recent Formulation Advances and Therapeutic Usefulness of Orally Disintegrating Tablets (ODTs)
by: Maimoona Chinwala
Published: (2020-10-01)