Functional homogeneity and specificity of topological modules in human proteome

Functional homogeneity and specificity of topological modules in human proteome

Abstract Background Functional modules in protein-protein interaction networks (PPIN) are defined by maximal sets of functionally associated proteins and are vital to understanding cellular mechanisms and identifying disease associated proteins. Topological modules of the human proteome have been sh...

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Bibliographic Details
Main Authors: Rama Kaalia, Jagath C. Rajapakse
Format: Article
Language:English
Published: BMC 2019-02-01
Series:BMC Bioinformatics
Subjects:
Topological modules
Functional modules
Physical PPI
Functional PPI
Functional enrichment analysis
Protein-protein interaction networks
Online Access:http://link.springer.com/article/10.1186/s12859-018-2549-8

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http://link.springer.com/article/10.1186/s12859-018-2549-8

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