Loss of Parkin reduces inflammatory arthritis by inhibiting p53 degradation
Parkin is associated with various inflammatory diseases, including Parkinson's disease (PD) and rheumatoid arthritis (RA). However, the precise role of Parkin in RA is unclear. The present study addressed this issue by comparing the development of RA between non-transgenic (non-Tg) mice and PAR...
Main Authors: | Yu Yeon Jung, Dong Ju Son, Hye Lim Lee, Dae Hwan Kim, Min Jong Song, Young Wan Ham, Youngsoo Kim, Sang Bae Han, Mi Hee Park, Jin Tae Hong |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2017-08-01
|
Series: | Redox Biology |
Online Access: | http://www.sciencedirect.com/science/article/pii/S221323171630427X |
Similar Items
-
Loss of parkin reduces lung tumor development by blocking p21 degradation.
by: Kyung-Ran Park, et al.
Published: (2019-01-01) -
Parkin deficiency prevents chronic ethanol-induced hepatic lipid accumulation through β-catenin accumulation
by: Dong Hun Lee, et al.
Published: (2019-08-01) -
Metformin Restores Parkin-Mediated Mitophagy, Suppressed by Cytosolic p53
by: Young Mi Song, et al.
Published: (2016-01-01) -
Parkin promotes degradation of the mitochondrial pro-apoptotic ARTS protein.
by: Stav Kemeny, et al.
Published: (2012-01-01) -
MUL1 acts in parallel to the PINK1/parkin pathway in regulating mitofusin and compensates for loss of PINK1/parkin
by: Jina Yun, et al.
Published: (2014-06-01)