Antineutrophil cytoplasmic antibody-associated vasculitis in a patient with diffuse scleroderma
Scleroderma is a multiorgan connective tissue disease characterized by autoantibody production and fibroproliferative stenosis of the microvasculature. The development of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis in patients with scleroderma is a rare association. Renal and pu...
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Wolters Kluwer Medknow Publications
2021-01-01
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Online Access: | http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2021;volume=16;issue=2;spage=217;epage=220;aulast=Shiva |
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doaj-8e3c8e9e7bbb4ccebeaef37b1c929c742021-07-07T10:50:42ZengWolters Kluwer Medknow PublicationsIndian Journal of Rheumatology0973-36980973-37012021-01-0116221722010.4103/injr.injr_84_20Antineutrophil cytoplasmic antibody-associated vasculitis in a patient with diffuse sclerodermaB N Shiva PrasadH A Karthik UralaScleroderma is a multiorgan connective tissue disease characterized by autoantibody production and fibroproliferative stenosis of the microvasculature. The development of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis in patients with scleroderma is a rare association. Renal and pulmonary complications occur more frequently than expected in scleroderma/ANCA-associated vasculitis overlap. The definitive diagnosis usually made based on autoantibody titers and biopsy of involved tissue. We present a case of diffuse scleroderma with ANCA-associated vasculitis presenting with neurological symptoms.http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2021;volume=16;issue=2;spage=217;epage=220;aulast=Shivaantineutrophil cytoplasmic antibody-associated vasculitisantimyeloperoxidase antibodiesdiffuse sclerodermaneuropathy |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
B N Shiva Prasad H A Karthik Urala |
spellingShingle |
B N Shiva Prasad H A Karthik Urala Antineutrophil cytoplasmic antibody-associated vasculitis in a patient with diffuse scleroderma Indian Journal of Rheumatology antineutrophil cytoplasmic antibody-associated vasculitis antimyeloperoxidase antibodies diffuse scleroderma neuropathy |
author_facet |
B N Shiva Prasad H A Karthik Urala |
author_sort |
B N Shiva Prasad |
title |
Antineutrophil cytoplasmic antibody-associated vasculitis in a patient with diffuse scleroderma |
title_short |
Antineutrophil cytoplasmic antibody-associated vasculitis in a patient with diffuse scleroderma |
title_full |
Antineutrophil cytoplasmic antibody-associated vasculitis in a patient with diffuse scleroderma |
title_fullStr |
Antineutrophil cytoplasmic antibody-associated vasculitis in a patient with diffuse scleroderma |
title_full_unstemmed |
Antineutrophil cytoplasmic antibody-associated vasculitis in a patient with diffuse scleroderma |
title_sort |
antineutrophil cytoplasmic antibody-associated vasculitis in a patient with diffuse scleroderma |
publisher |
Wolters Kluwer Medknow Publications |
series |
Indian Journal of Rheumatology |
issn |
0973-3698 0973-3701 |
publishDate |
2021-01-01 |
description |
Scleroderma is a multiorgan connective tissue disease characterized by autoantibody production and fibroproliferative stenosis of the microvasculature. The development of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis in patients with scleroderma is a rare association. Renal and pulmonary complications occur more frequently than expected in scleroderma/ANCA-associated vasculitis overlap. The definitive diagnosis usually made based on autoantibody titers and biopsy of involved tissue. We present a case of diffuse scleroderma with ANCA-associated vasculitis presenting with neurological symptoms. |
topic |
antineutrophil cytoplasmic antibody-associated vasculitis antimyeloperoxidase antibodies diffuse scleroderma neuropathy |
url |
http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2021;volume=16;issue=2;spage=217;epage=220;aulast=Shiva |
work_keys_str_mv |
AT bnshivaprasad antineutrophilcytoplasmicantibodyassociatedvasculitisinapatientwithdiffusescleroderma AT hakarthikurala antineutrophilcytoplasmicantibodyassociatedvasculitisinapatientwithdiffusescleroderma |
_version_ |
1721316403873579008 |