SOX9 is a dose-dependent metastatic fate determinant in melanoma

SOX9 is a dose-dependent metastatic fate determinant in melanoma

Abstract Background In this research, we aimed to resolve contradictory results whether SOX9 plays a positive or negative role in melanoma progression and determine whether SOX9 and its closely related member SOX10 share the same or distinct targets in mediating their functions in melanoma. Methods...

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Bibliographic Details
Main Authors: Xintao Yang, Rui Liang, Chunxi Liu, Jessica Aijia Liu, May Pui Lai Cheung, Xuelai Liu, On Ying Man, Xin-Yuan Guan, Hong Lok Lung, Martin Cheung
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
SOX9; SOX10
NEDD9
RHOA
RAC1
Melanoma
Metastatic
Online Access:http://link.springer.com/article/10.1186/s13046-018-0998-6

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