Bioresponsive Hydrogels: Chemical Strategies and Perspectives in Tissue Engineering
Disease, trauma, and aging account for a significant number of clinical disorders. Regenerative medicine is emerging as a very promising therapeutic option. The design and development of new cell-customised biomaterials able to mimic extracellular matrix (ECM) functionalities represents one of the m...
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doaj-8e6c2319e146453f8160f000c21239952020-11-24T20:53:45ZengMDPI AGGels2310-28612016-10-01242810.3390/gels2040028gels2040028Bioresponsive Hydrogels: Chemical Strategies and Perspectives in Tissue EngineeringAntonella Sgambato0Laura Cipolla1Laura Russo2Department of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milano, ItalyDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milano, ItalyDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milano, ItalyDisease, trauma, and aging account for a significant number of clinical disorders. Regenerative medicine is emerging as a very promising therapeutic option. The design and development of new cell-customised biomaterials able to mimic extracellular matrix (ECM) functionalities represents one of the major strategies to control the cell fate and stimulate tissue regeneration. Recently, hydrogels have received a considerable interest for their use in the modulation and control of cell fate during the regeneration processes. Several synthetic bioresponsive hydrogels are being developed in order to facilitate cell-matrix and cell-cell interactions. In this review, new strategies and future perspectives of such synthetic cell microenvironments will be highlighted.http://www.mdpi.com/2310-2861/2/4/28hydrogelstissue engineeringbioconjugation |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Antonella Sgambato Laura Cipolla Laura Russo |
spellingShingle |
Antonella Sgambato Laura Cipolla Laura Russo Bioresponsive Hydrogels: Chemical Strategies and Perspectives in Tissue Engineering Gels hydrogels tissue engineering bioconjugation |
author_facet |
Antonella Sgambato Laura Cipolla Laura Russo |
author_sort |
Antonella Sgambato |
title |
Bioresponsive Hydrogels: Chemical Strategies and Perspectives in Tissue Engineering |
title_short |
Bioresponsive Hydrogels: Chemical Strategies and Perspectives in Tissue Engineering |
title_full |
Bioresponsive Hydrogels: Chemical Strategies and Perspectives in Tissue Engineering |
title_fullStr |
Bioresponsive Hydrogels: Chemical Strategies and Perspectives in Tissue Engineering |
title_full_unstemmed |
Bioresponsive Hydrogels: Chemical Strategies and Perspectives in Tissue Engineering |
title_sort |
bioresponsive hydrogels: chemical strategies and perspectives in tissue engineering |
publisher |
MDPI AG |
series |
Gels |
issn |
2310-2861 |
publishDate |
2016-10-01 |
description |
Disease, trauma, and aging account for a significant number of clinical disorders. Regenerative medicine is emerging as a very promising therapeutic option. The design and development of new cell-customised biomaterials able to mimic extracellular matrix (ECM) functionalities represents one of the major strategies to control the cell fate and stimulate tissue regeneration. Recently, hydrogels have received a considerable interest for their use in the modulation and control of cell fate during the regeneration processes. Several synthetic bioresponsive hydrogels are being developed in order to facilitate cell-matrix and cell-cell interactions. In this review, new strategies and future perspectives of such synthetic cell microenvironments will be highlighted. |
topic |
hydrogels tissue engineering bioconjugation |
url |
http://www.mdpi.com/2310-2861/2/4/28 |
work_keys_str_mv |
AT antonellasgambato bioresponsivehydrogelschemicalstrategiesandperspectivesintissueengineering AT lauracipolla bioresponsivehydrogelschemicalstrategiesandperspectivesintissueengineering AT laurarusso bioresponsivehydrogelschemicalstrategiesandperspectivesintissueengineering |
_version_ |
1716796249308397568 |