Comparison of the in-vivo effect of two tranexamic acid doses on fibrinolysis parameters in adults undergoing valvular cardiac surgery with cardiopulmonary bypass - a pilot investigation

Comparison of the in-vivo effect of two tranexamic acid doses on fibrinolysis parameters in adults undergoing valvular cardiac surgery with cardiopulmonary bypass - a pilot investigation

Abstract Background The blood saving efficacy of TXA in cardiac surgery has been proved in several studies, but TXA dosing regimens were varied in those studies. Therefore, we performed this study to investigate if there is a dose dependent in-vivo effect of TXA on fibrinolysis parameters by measure...

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Bibliographic Details
Main Authors: Zhen-feng Zhou, Wen Zhai, Li-na Yu, Kai Sun, Li-hong Sun, Xiu-fang Xing, Min Yan
Format: Article
Language:English
Published: BMC 2021-02-01
Series:BMC Anesthesiology
Subjects:
Tranexamic acid
Fibrinolysis
Tissue plasminogen activator
Cardiac surger
Online Access:https://doi.org/10.1186/s12871-021-01234-8

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