Enhanced susceptibility to spontaneous seizures of noda epileptic rats by loss of synaptic zn(2+).

Enhanced susceptibility to spontaneous seizures of noda epileptic rats by loss of synaptic zn(2+).

Zinc homeostasis in the brain is associated with the etiology and manifestation of epileptic seizures. Adult Noda epileptic rats (NER, >12-week-old) exhibit spontaneously generalized tonic-clonic convulsion about once a day. To pursue the involvement of synaptic Zn(2+) signal in susceptibility to...

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Bibliographic Details
Main Authors: Atsushi Takeda, Masashi Iida, Masaki Ando, Masatoshi Nakamura, Haruna Tamano, Naoto Oku
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3741169?pdf=render

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http://europepmc.org/articles/PMC3741169?pdf=render

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