The Acinetobacter baumannii disinfectant resistance protein, AmvA, is a spermidine and spermine efflux pump
Francesca Short et al. identify natural polyamines as substrates for a drug efflux pump in the clinically-relevant pathogen, Acinetobacter baumannii. Their results suggest that efflux pumps now known to be involved in drug resistance may have originated as polyamine transporters.
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2021-09-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-021-02629-6 |