Biocatalytic Oxidation of Alcohols

Biocatalytic Oxidation of Alcohols

Enzymatic methods for the oxidation of alcohols are critically reviewed. Dehydrogenases and oxidases are the most prominent biocatalysts, enabling the selective oxidation of primary alcohols into aldehydes or acids. In the case of secondary alcohols, region and/or enantioselective oxidation is possi...

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Main Authors: Hendrik Puetz, Eva Puchľová, Kvetoslava Vranková, Frank Hollmann
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Catalysts
Subjects:
alcohols
alcohol oxidation
alcohol dehydrogenases
alcohol oxidases
kinetic resolution
deracemization
Online Access:https://www.mdpi.com/2073-4344/10/9/952
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spelling doaj-8e88afbe63ce4f90ba706e4eb8973b2e2020-11-25T03:52:41ZengMDPI AGCatalysts2073-43442020-08-011095295210.3390/catal10090952Biocatalytic Oxidation of AlcoholsHendrik Puetz0Eva Puchľová1Kvetoslava Vranková2Frank Hollmann3Department of Biotechnology, Delft University of Technology, van der Maasweg 9, 2629 HZ Delft, The NetherlandsAxxence Slovakia s.r.o, Mickiewiczova 9, 81107 Bratislava, SlovakiaAxxence Slovakia s.r.o, Mickiewiczova 9, 81107 Bratislava, SlovakiaDepartment of Biotechnology, Delft University of Technology, van der Maasweg 9, 2629 HZ Delft, The NetherlandsEnzymatic methods for the oxidation of alcohols are critically reviewed. Dehydrogenases and oxidases are the most prominent biocatalysts, enabling the selective oxidation of primary alcohols into aldehydes or acids. In the case of secondary alcohols, region and/or enantioselective oxidation is possible. In this contribution, we outline the current state-of-the-art and discuss current limitations and promising solutions.https://www.mdpi.com/2073-4344/10/9/952alcoholsalcohol oxidationalcohol dehydrogenasesalcohol oxidaseskinetic resolutionderacemization
collection DOAJ
language English
format Article
sources DOAJ
author Hendrik Puetz
Eva Puchľová
Kvetoslava Vranková
Frank Hollmann
spellingShingle Hendrik Puetz
Eva Puchľová
Kvetoslava Vranková
Frank Hollmann
Biocatalytic Oxidation of Alcohols
Catalysts
alcohols
alcohol oxidation
alcohol dehydrogenases
alcohol oxidases
kinetic resolution
deracemization
author_facet Hendrik Puetz
Eva Puchľová
Kvetoslava Vranková
Frank Hollmann
author_sort Hendrik Puetz
title Biocatalytic Oxidation of Alcohols
title_short Biocatalytic Oxidation of Alcohols
title_full Biocatalytic Oxidation of Alcohols
title_fullStr Biocatalytic Oxidation of Alcohols
title_full_unstemmed Biocatalytic Oxidation of Alcohols
title_sort biocatalytic oxidation of alcohols
publisher MDPI AG
series Catalysts
issn 2073-4344
publishDate 2020-08-01
description Enzymatic methods for the oxidation of alcohols are critically reviewed. Dehydrogenases and oxidases are the most prominent biocatalysts, enabling the selective oxidation of primary alcohols into aldehydes or acids. In the case of secondary alcohols, region and/or enantioselective oxidation is possible. In this contribution, we outline the current state-of-the-art and discuss current limitations and promising solutions.
topic alcohols
alcohol oxidation
alcohol dehydrogenases
alcohol oxidases
kinetic resolution
deracemization
url https://www.mdpi.com/2073-4344/10/9/952
work_keys_str_mv AT hendrikpuetz biocatalyticoxidationofalcohols
AT evapuchlova biocatalyticoxidationofalcohols
AT kvetoslavavrankova biocatalyticoxidationofalcohols
AT frankhollmann biocatalyticoxidationofalcohols
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