WNT5a-ROR Signaling Is Essential for Alveologenesis

WNT5a-ROR Signaling Is Essential for Alveologenesis

WNT5a is a mainly &#8220;non-canonical&#8221; WNT ligand whose dysregulation is observed in lung diseases such as idiopathic pulmonary fibrosis (IPF), chronic obstructive pulmonary disease (COPD) and asthma. Germline deletion of <i>Wnt5a</i> disrupts embryonic lung development. H...

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Bibliographic Details
Main Authors: Changgong Li, Susan M Smith, Neil Peinado, Feng Gao, Wei Li, Matt K Lee, Beiyun Zhou, Saverio Bellusci, Gloria S Pryhuber, Hsin-Yi Henry Ho, Zea Borok, Parviz Minoo
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Cells
Subjects:
wnt5a
ror
lung
alveologenesis
secondary crest myofibroblast
migration
Online Access:https://www.mdpi.com/2073-4409/9/2/384

Internet

https://www.mdpi.com/2073-4409/9/2/384

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