Blood dopamine level enhanced by caffeine in men after treadmill running

The aim of this study was to investigate the plasma dopamine and serum serotonin levels in humans with and without caffeine (CAFF) ingestion during treadmill running exercise. Thirty male volunteers participated in the randomized experiment involving two groups: CON (n = 15, 200 mL of tap water) ver...

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Main Authors: Jeong-Beom Lee, Hye-Jin Lee, Seung-Jea Lee, Tae-Wook Kim
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Chinese Journal of Physiology
Subjects:
Online Access:http://www.cjphysiology.org/article.asp?issn=0304-4920;year=2019;volume=62;issue=6;spage=279;epage=284;aulast=Lee
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spelling doaj-8ecc06173cc84364aa4428d68f6fc5962021-04-20T08:40:55ZengWolters Kluwer Medknow PublicationsChinese Journal of Physiology0304-49202666-00592019-01-0162627928410.4103/CJP.CJP_59_19Blood dopamine level enhanced by caffeine in men after treadmill runningJeong-Beom LeeHye-Jin LeeSeung-Jea LeeTae-Wook KimThe aim of this study was to investigate the plasma dopamine and serum serotonin levels in humans with and without caffeine (CAFF) ingestion during treadmill running exercise. Thirty male volunteers participated in the randomized experiment involving two groups: CON (n = 15, 200 mL of tap water) versus CAFF (n = 15, 3 mg/kg CAFF and 200 mL tap water). After treadmill running, the dopamine level was significantly increased in the CAFF group (P < 0.01) and was significantly higher than in the CON group (P < 0.01). Serotonin was significantly increased in both groups after treadmill running (P < 0.05). However, serotonin levels showed no significant statistical difference between the groups. Prolactin and cortisol were significantly increased in both groups after treadmill running (P < 0.01). However, there was no significant statistical difference between groups. β-endorphin level was significantly increased in the CAFF group at after treadmill running (P < 0.01) and was significantly higher than in CON after treadmill running (P < 0.01). In conclusion, 3 mg/kg CAFF ingestion before treadmill running stimulated dopamine release without inhibiting serotonin, which may reduce central fatigue.http://www.cjphysiology.org/article.asp?issn=0304-4920;year=2019;volume=62;issue=6;spage=279;epage=284;aulast=Leecaffeinedopamineprolactinserotoninβ-endorphin
collection DOAJ
language English
format Article
sources DOAJ
author Jeong-Beom Lee
Hye-Jin Lee
Seung-Jea Lee
Tae-Wook Kim
spellingShingle Jeong-Beom Lee
Hye-Jin Lee
Seung-Jea Lee
Tae-Wook Kim
Blood dopamine level enhanced by caffeine in men after treadmill running
Chinese Journal of Physiology
caffeine
dopamine
prolactin
serotonin
β-endorphin
author_facet Jeong-Beom Lee
Hye-Jin Lee
Seung-Jea Lee
Tae-Wook Kim
author_sort Jeong-Beom Lee
title Blood dopamine level enhanced by caffeine in men after treadmill running
title_short Blood dopamine level enhanced by caffeine in men after treadmill running
title_full Blood dopamine level enhanced by caffeine in men after treadmill running
title_fullStr Blood dopamine level enhanced by caffeine in men after treadmill running
title_full_unstemmed Blood dopamine level enhanced by caffeine in men after treadmill running
title_sort blood dopamine level enhanced by caffeine in men after treadmill running
publisher Wolters Kluwer Medknow Publications
series Chinese Journal of Physiology
issn 0304-4920
2666-0059
publishDate 2019-01-01
description The aim of this study was to investigate the plasma dopamine and serum serotonin levels in humans with and without caffeine (CAFF) ingestion during treadmill running exercise. Thirty male volunteers participated in the randomized experiment involving two groups: CON (n = 15, 200 mL of tap water) versus CAFF (n = 15, 3 mg/kg CAFF and 200 mL tap water). After treadmill running, the dopamine level was significantly increased in the CAFF group (P < 0.01) and was significantly higher than in the CON group (P < 0.01). Serotonin was significantly increased in both groups after treadmill running (P < 0.05). However, serotonin levels showed no significant statistical difference between the groups. Prolactin and cortisol were significantly increased in both groups after treadmill running (P < 0.01). However, there was no significant statistical difference between groups. β-endorphin level was significantly increased in the CAFF group at after treadmill running (P < 0.01) and was significantly higher than in CON after treadmill running (P < 0.01). In conclusion, 3 mg/kg CAFF ingestion before treadmill running stimulated dopamine release without inhibiting serotonin, which may reduce central fatigue.
topic caffeine
dopamine
prolactin
serotonin
β-endorphin
url http://www.cjphysiology.org/article.asp?issn=0304-4920;year=2019;volume=62;issue=6;spage=279;epage=284;aulast=Lee
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