Blood dopamine level enhanced by caffeine in men after treadmill running
The aim of this study was to investigate the plasma dopamine and serum serotonin levels in humans with and without caffeine (CAFF) ingestion during treadmill running exercise. Thirty male volunteers participated in the randomized experiment involving two groups: CON (n = 15, 200 mL of tap water) ver...
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Wolters Kluwer Medknow Publications
2019-01-01
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doaj-8ecc06173cc84364aa4428d68f6fc5962021-04-20T08:40:55ZengWolters Kluwer Medknow PublicationsChinese Journal of Physiology0304-49202666-00592019-01-0162627928410.4103/CJP.CJP_59_19Blood dopamine level enhanced by caffeine in men after treadmill runningJeong-Beom LeeHye-Jin LeeSeung-Jea LeeTae-Wook KimThe aim of this study was to investigate the plasma dopamine and serum serotonin levels in humans with and without caffeine (CAFF) ingestion during treadmill running exercise. Thirty male volunteers participated in the randomized experiment involving two groups: CON (n = 15, 200 mL of tap water) versus CAFF (n = 15, 3 mg/kg CAFF and 200 mL tap water). After treadmill running, the dopamine level was significantly increased in the CAFF group (P < 0.01) and was significantly higher than in the CON group (P < 0.01). Serotonin was significantly increased in both groups after treadmill running (P < 0.05). However, serotonin levels showed no significant statistical difference between the groups. Prolactin and cortisol were significantly increased in both groups after treadmill running (P < 0.01). However, there was no significant statistical difference between groups. β-endorphin level was significantly increased in the CAFF group at after treadmill running (P < 0.01) and was significantly higher than in CON after treadmill running (P < 0.01). In conclusion, 3 mg/kg CAFF ingestion before treadmill running stimulated dopamine release without inhibiting serotonin, which may reduce central fatigue.http://www.cjphysiology.org/article.asp?issn=0304-4920;year=2019;volume=62;issue=6;spage=279;epage=284;aulast=Leecaffeinedopamineprolactinserotoninβ-endorphin |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Jeong-Beom Lee Hye-Jin Lee Seung-Jea Lee Tae-Wook Kim |
spellingShingle |
Jeong-Beom Lee Hye-Jin Lee Seung-Jea Lee Tae-Wook Kim Blood dopamine level enhanced by caffeine in men after treadmill running Chinese Journal of Physiology caffeine dopamine prolactin serotonin β-endorphin |
author_facet |
Jeong-Beom Lee Hye-Jin Lee Seung-Jea Lee Tae-Wook Kim |
author_sort |
Jeong-Beom Lee |
title |
Blood dopamine level enhanced by caffeine in men after treadmill running |
title_short |
Blood dopamine level enhanced by caffeine in men after treadmill running |
title_full |
Blood dopamine level enhanced by caffeine in men after treadmill running |
title_fullStr |
Blood dopamine level enhanced by caffeine in men after treadmill running |
title_full_unstemmed |
Blood dopamine level enhanced by caffeine in men after treadmill running |
title_sort |
blood dopamine level enhanced by caffeine in men after treadmill running |
publisher |
Wolters Kluwer Medknow Publications |
series |
Chinese Journal of Physiology |
issn |
0304-4920 2666-0059 |
publishDate |
2019-01-01 |
description |
The aim of this study was to investigate the plasma dopamine and serum serotonin levels in humans with and without caffeine (CAFF) ingestion during treadmill running exercise. Thirty male volunteers participated in the randomized experiment involving two groups: CON (n = 15, 200 mL of tap water) versus CAFF (n = 15, 3 mg/kg CAFF and 200 mL tap water). After treadmill running, the dopamine level was significantly increased in the CAFF group (P < 0.01) and was significantly higher than in the CON group (P < 0.01). Serotonin was significantly increased in both groups after treadmill running (P < 0.05). However, serotonin levels showed no significant statistical difference between the groups. Prolactin and cortisol were significantly increased in both groups after treadmill running (P < 0.01). However, there was no significant statistical difference between groups. β-endorphin level was significantly increased in the CAFF group at after treadmill running (P < 0.01) and was significantly higher than in CON after treadmill running (P < 0.01). In conclusion, 3 mg/kg CAFF ingestion before treadmill running stimulated dopamine release without inhibiting serotonin, which may reduce central fatigue. |
topic |
caffeine dopamine prolactin serotonin β-endorphin |
url |
http://www.cjphysiology.org/article.asp?issn=0304-4920;year=2019;volume=62;issue=6;spage=279;epage=284;aulast=Lee |
work_keys_str_mv |
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