17βH-Periplogenin, a cardiac aglycone from the root bark of Periploca sepium Bunge

17βH-Periplogenin, a cardiac aglycone from the root bark of Periploca sepium Bunge

The title compound {systematic name: 4-[(3S,5S,8R,9S,10R,13R,14S,17S)-3,5,14-trihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl]furan-2(5H)-one}, C23H34O5, was isolated from the roots of Periploca sepium Bunge, a famous Chinese traditional herbal medicine. The three six-membere...

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Main Authors: Yu-Wei Zhang, Yong-Li Bao, Yin Wu, Chun-Lei Yu, Yu-Xin Li
Format: Article
Language:English
Published: International Union of Crystallography 2012-06-01
Series:Acta Crystallographica Section E
Online Access:http://scripts.iucr.org/cgi-bin/paper?S1600536812018521
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spelling doaj-8ee8ddba08094df7bc22ea156218a5c52020-11-25T01:27:46ZengInternational Union of CrystallographyActa Crystallographica Section E1600-53682012-06-01686o1582o158310.1107/S160053681201852117βH-Periplogenin, a cardiac aglycone from the root bark of Periploca sepium BungeYu-Wei ZhangYong-Li BaoYin WuChun-Lei YuYu-Xin LiThe title compound {systematic name: 4-[(3S,5S,8R,9S,10R,13R,14S,17S)-3,5,14-trihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl]furan-2(5H)-one}, C23H34O5, was isolated from the roots of Periploca sepium Bunge, a famous Chinese traditional herbal medicine. The three six-membered rings adopt chair conformations, the cyclopentane ring displays an approximate envelope conformation (with the C atom bearing the methyl substituent at the flap) and the five-membered lactone ring adopts an essentially planar [maximum deviation of 0.004 (8) Å] conformation. In the crystal, molecules are linked into helical chains along [010] by O—H...O hydrogen bonds and weak C—H...O interactions. Two intramolecular O—H...O hydrogen bonds are also present. http://scripts.iucr.org/cgi-bin/paper?S1600536812018521
collection DOAJ
language English
format Article
sources DOAJ
author Yu-Wei Zhang
Yong-Li Bao
Yin Wu
Chun-Lei Yu
Yu-Xin Li
spellingShingle Yu-Wei Zhang
Yong-Li Bao
Yin Wu
Chun-Lei Yu
Yu-Xin Li
17βH-Periplogenin, a cardiac aglycone from the root bark of Periploca sepium Bunge
Acta Crystallographica Section E
author_facet Yu-Wei Zhang
Yong-Li Bao
Yin Wu
Chun-Lei Yu
Yu-Xin Li
author_sort Yu-Wei Zhang
title 17βH-Periplogenin, a cardiac aglycone from the root bark of Periploca sepium Bunge
title_short 17βH-Periplogenin, a cardiac aglycone from the root bark of Periploca sepium Bunge
title_full 17βH-Periplogenin, a cardiac aglycone from the root bark of Periploca sepium Bunge
title_fullStr 17βH-Periplogenin, a cardiac aglycone from the root bark of Periploca sepium Bunge
title_full_unstemmed 17βH-Periplogenin, a cardiac aglycone from the root bark of Periploca sepium Bunge
title_sort 17βh-periplogenin, a cardiac aglycone from the root bark of periploca sepium bunge
publisher International Union of Crystallography
series Acta Crystallographica Section E
issn 1600-5368
publishDate 2012-06-01
description The title compound {systematic name: 4-[(3S,5S,8R,9S,10R,13R,14S,17S)-3,5,14-trihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl]furan-2(5H)-one}, C23H34O5, was isolated from the roots of Periploca sepium Bunge, a famous Chinese traditional herbal medicine. The three six-membered rings adopt chair conformations, the cyclopentane ring displays an approximate envelope conformation (with the C atom bearing the methyl substituent at the flap) and the five-membered lactone ring adopts an essentially planar [maximum deviation of 0.004 (8) Å] conformation. In the crystal, molecules are linked into helical chains along [010] by O—H...O hydrogen bonds and weak C—H...O interactions. Two intramolecular O—H...O hydrogen bonds are also present.
url http://scripts.iucr.org/cgi-bin/paper?S1600536812018521
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AT yonglibao 17amp946hperiplogeninacardiacaglyconefromtherootbarkofperiplocasepiumbunge
AT yinwu 17amp946hperiplogeninacardiacaglyconefromtherootbarkofperiplocasepiumbunge
AT chunleiyu 17amp946hperiplogeninacardiacaglyconefromtherootbarkofperiplocasepiumbunge
AT yuxinli 17amp946hperiplogeninacardiacaglyconefromtherootbarkofperiplocasepiumbunge
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