CT and MRI characteristics of presumptive hypervitaminosis A in a cat

Case summary A rescued stray cat with an unknown history was examined for non-ambulatory paraparesis in the hindlimbs. Survey radiographs revealed typical findings of hypervitaminosis A, characterised by vertebral exostoses and extensive osteophytes, mainly in the cervicothoracic spine. CT findings...

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Main Authors: Yoshihiko Yu, Atsushi Sugiyama, Takashi Kuniya, Daisuke Hasegawa
Format: Article
Language:English
Published: SAGE Publishing 2021-03-01
Series:Journal of Feline Medicine and Surgery Open Reports
Online Access:https://doi.org/10.1177/2055116921990301
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spelling doaj-8ef8909ea529405fae57b908ff47e1d22021-03-16T21:33:44ZengSAGE PublishingJournal of Feline Medicine and Surgery Open Reports2055-11692021-03-01710.1177/2055116921990301CT and MRI characteristics of presumptive hypervitaminosis A in a catYoshihiko Yu0Atsushi Sugiyama1Takashi Kuniya2Daisuke Hasegawa3Laboratory of Veterinary Radiology, Nippon Veterinary and Life Science University, Musashino, Tokyo, JapanSuruga Animal Hospital, Shizuoka, JapanKaba Veterinary Clinic, Hamamatsu, Shizuoka, JapanThe Research Center for Animal Life Science, Nippon Veterinary and Life Science University, Musashino, Tokyo, JapanCase summary A rescued stray cat with an unknown history was examined for non-ambulatory paraparesis in the hindlimbs. Survey radiographs revealed typical findings of hypervitaminosis A, characterised by vertebral exostoses and extensive osteophytes, mainly in the cervicothoracic spine. CT findings were consistent with the radiographic findings, and CT-based volume rendering and virtual endoscopy into the vertebral canal were created for three-dimensional visualisation of the lesion. MRI revealed a focal and mild dilation of the central canal of the spinal cord. Although the clinical diagnosis of hypervitaminosis A is based on an unusual dietary history and characteristic radiographic findings, the history of this cat was unknown and serum concentrations of vitamin A were unremarkable, when measured >1 month after rescue. However, other possible differential diagnoses were thought to be unlikely and clinical signs never worsened, and thus, hypervitaminosis A was presumed. Relevance and novel information To our knowledge, this is the first report to present the CT and MRI characteristics of a cat with suspected hypervitaminosis A.https://doi.org/10.1177/2055116921990301
collection DOAJ
language English
format Article
sources DOAJ
author Yoshihiko Yu
Atsushi Sugiyama
Takashi Kuniya
Daisuke Hasegawa
spellingShingle Yoshihiko Yu
Atsushi Sugiyama
Takashi Kuniya
Daisuke Hasegawa
CT and MRI characteristics of presumptive hypervitaminosis A in a cat
Journal of Feline Medicine and Surgery Open Reports
author_facet Yoshihiko Yu
Atsushi Sugiyama
Takashi Kuniya
Daisuke Hasegawa
author_sort Yoshihiko Yu
title CT and MRI characteristics of presumptive hypervitaminosis A in a cat
title_short CT and MRI characteristics of presumptive hypervitaminosis A in a cat
title_full CT and MRI characteristics of presumptive hypervitaminosis A in a cat
title_fullStr CT and MRI characteristics of presumptive hypervitaminosis A in a cat
title_full_unstemmed CT and MRI characteristics of presumptive hypervitaminosis A in a cat
title_sort ct and mri characteristics of presumptive hypervitaminosis a in a cat
publisher SAGE Publishing
series Journal of Feline Medicine and Surgery Open Reports
issn 2055-1169
publishDate 2021-03-01
description Case summary A rescued stray cat with an unknown history was examined for non-ambulatory paraparesis in the hindlimbs. Survey radiographs revealed typical findings of hypervitaminosis A, characterised by vertebral exostoses and extensive osteophytes, mainly in the cervicothoracic spine. CT findings were consistent with the radiographic findings, and CT-based volume rendering and virtual endoscopy into the vertebral canal were created for three-dimensional visualisation of the lesion. MRI revealed a focal and mild dilation of the central canal of the spinal cord. Although the clinical diagnosis of hypervitaminosis A is based on an unusual dietary history and characteristic radiographic findings, the history of this cat was unknown and serum concentrations of vitamin A were unremarkable, when measured >1 month after rescue. However, other possible differential diagnoses were thought to be unlikely and clinical signs never worsened, and thus, hypervitaminosis A was presumed. Relevance and novel information To our knowledge, this is the first report to present the CT and MRI characteristics of a cat with suspected hypervitaminosis A.
url https://doi.org/10.1177/2055116921990301
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