DNMT3A Mutations in Patients with Acute Myeloid Leukemia in South Brazil

Acute myeloid leukemia (AML) is a complex and heterogeneous hematopoietic tissue neoplasm. Several molecular markers have been described that help to classify AML patients into risk groups. DNA methyltransferase 3A (DNMT3A) gene mutations have been recently identified in about 22% of AML patients an...

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Bibliographic Details
Main Authors: Annelise Pezzi, Lauro Moraes, Vanessa Valim, Bruna Amorin, Gabriela Melchiades, Fernanda Oliveira, Maria Aparecida da Silva, Ursula Matte, Maria S. Pombo-de-Oliveira, Rosane Bittencourt, Liane Daudt, Lúcia Silla
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Advances in Hematology
Online Access:http://dx.doi.org/10.1155/2012/697691