Fibroblasts from the Human Skin Dermo-Hypodermal Junction are Distinct from Dermal Papillary and Reticular Fibroblasts and from Mesenchymal Stem Cells and Exhibit a Specific Molecular Profile Related to Extracellular Matrix Organization and Modeling

Fibroblasts from the Human Skin Dermo-Hypodermal Junction are Distinct from Dermal Papillary and Reticular Fibroblasts and from Mesenchymal Stem Cells and Exhibit a Specific Molecular Profile Related to Extracellular Matrix Organization and Modeling

Human skin dermis contains fibroblast subpopulations in which characterization is crucial due to their roles in extracellular matrix (ECM) biology. This study investigates the properties of fibroblasts localized at the frontier of deep dermis and hypodermis, i.e., dermo-hypodermal junction fibroblas...

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Bibliographic Details
Main Authors: Valérie Haydont, Véronique Neiveyans, Philippe Perez, Élodie Busson, Jean-Jacques Lataillade, Daniel Asselineau, Nicolas O. Fortunel
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Cells
Subjects:
human dermis
fibroblasts
extracellular matrix (ecm)
dermo-hypodermal junction
papillary fibroblasts (fp)
reticular fibroblasts (fr)
tenascin c (tnc)
mesenchymal stem cells (mscs)
Online Access:https://www.mdpi.com/2073-4409/9/2/368

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https://www.mdpi.com/2073-4409/9/2/368

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