Investigation of the response to the enterobacterial common antigen after typhoid vaccination

Antibodies against the Salmonella typhi enterobacterial common antigen (ECA) and the O and H antigens were investigated in sera from healthy male subjects who had been previously vaccinated with the typhoid vaccine. No serological response to ECA was observed. Sera from subjects not previously vacci...

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Main Authors: Arlete M. Milhomem, ítalo Suassuna
Format: Article
Language:English
Published: Sociedade Brasileira de Medicina Tropical (SBMT) 1987-03-01
Series:Revista da Sociedade Brasileira de Medicina Tropical
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821987000100002
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spelling doaj-8f07bee2745f4bfdbc8b387f020da22c2020-11-25T02:27:14ZengSociedade Brasileira de Medicina Tropical (SBMT)Revista da Sociedade Brasileira de Medicina Tropical0037-86821678-98491987-03-01201712Investigation of the response to the enterobacterial common antigen after typhoid vaccinationArlete M. Milhomemítalo SuassunaAntibodies against the Salmonella typhi enterobacterial common antigen (ECA) and the O and H antigens were investigated in sera from healthy male subjects who had been previously vaccinated with the typhoid vaccine. No serological response to ECA was observed. Sera from subjects not previously vaccinated presented titers of ECA hemagglutinins which quantitatively were related to the presence ofH titers, but not to O agglutinins but with no statistical significance. The results are discussed in relation to the possible protective immunological mechanisms in typhoid fever.<br>Anticorpos contra o antígeno comum de enterobactérias (ECA) bem como contra os antigenos somáticos (O) e flagelar (H) de Salmonella typhi foram investigados no soro de recrutas do sexo masculino, após a vacinação. Não fo i detectada resposta humoral para ECA. Os soros obtidos antes da vacinação mostraram hemaglutininas para ECA acompanhando a presença de aglutininas para o antígeno H, ao contrário do que se observou em relação ao antígeno O. Discutem-se os resultados quanto ao possível mecanismo da imunoproteção da febre tifóide.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821987000100002Febre tifóideVacinaçãoAntigenos comuns de enterobactérias e O e H de Salmonella typhiTyphoid feverVaccineSalmonella typhiEnterobacterial common antigenO and H antigens
collection DOAJ
language English
format Article
sources DOAJ
author Arlete M. Milhomem
ítalo Suassuna
spellingShingle Arlete M. Milhomem
ítalo Suassuna
Investigation of the response to the enterobacterial common antigen after typhoid vaccination
Revista da Sociedade Brasileira de Medicina Tropical
Febre tifóide
Vacinação
Antigenos comuns de enterobactérias e O e H de Salmonella typhi
Typhoid fever
Vaccine
Salmonella typhi
Enterobacterial common antigen
O and H antigens
author_facet Arlete M. Milhomem
ítalo Suassuna
author_sort Arlete M. Milhomem
title Investigation of the response to the enterobacterial common antigen after typhoid vaccination
title_short Investigation of the response to the enterobacterial common antigen after typhoid vaccination
title_full Investigation of the response to the enterobacterial common antigen after typhoid vaccination
title_fullStr Investigation of the response to the enterobacterial common antigen after typhoid vaccination
title_full_unstemmed Investigation of the response to the enterobacterial common antigen after typhoid vaccination
title_sort investigation of the response to the enterobacterial common antigen after typhoid vaccination
publisher Sociedade Brasileira de Medicina Tropical (SBMT)
series Revista da Sociedade Brasileira de Medicina Tropical
issn 0037-8682
1678-9849
publishDate 1987-03-01
description Antibodies against the Salmonella typhi enterobacterial common antigen (ECA) and the O and H antigens were investigated in sera from healthy male subjects who had been previously vaccinated with the typhoid vaccine. No serological response to ECA was observed. Sera from subjects not previously vaccinated presented titers of ECA hemagglutinins which quantitatively were related to the presence ofH titers, but not to O agglutinins but with no statistical significance. The results are discussed in relation to the possible protective immunological mechanisms in typhoid fever.<br>Anticorpos contra o antígeno comum de enterobactérias (ECA) bem como contra os antigenos somáticos (O) e flagelar (H) de Salmonella typhi foram investigados no soro de recrutas do sexo masculino, após a vacinação. Não fo i detectada resposta humoral para ECA. Os soros obtidos antes da vacinação mostraram hemaglutininas para ECA acompanhando a presença de aglutininas para o antígeno H, ao contrário do que se observou em relação ao antígeno O. Discutem-se os resultados quanto ao possível mecanismo da imunoproteção da febre tifóide.
topic Febre tifóide
Vacinação
Antigenos comuns de enterobactérias e O e H de Salmonella typhi
Typhoid fever
Vaccine
Salmonella typhi
Enterobacterial common antigen
O and H antigens
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821987000100002
work_keys_str_mv AT arletemmilhomem investigationoftheresponsetotheenterobacterialcommonantigenaftertyphoidvaccination
AT italosuassuna investigationoftheresponsetotheenterobacterialcommonantigenaftertyphoidvaccination
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