Utilization of adipocyte-derived lipids and enhanced intracellular trafficking of fatty acids contribute to breast cancer progression

Utilization of adipocyte-derived lipids and enhanced intracellular trafficking of fatty acids contribute to breast cancer progression

Abstract Background To determine whether adipocyte-derived lipids could be transferred into breast cancer cells and investigate the underlying mechanisms of subsequent lipolysis and fatty acid trafficking in breast cancer cells. Methods A Transwell co-culture system was used in which human breast ca...

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Bibliographic Details
Main Authors: Dejuan Yang, Yunhai Li, Lei Xing, Yiqing Tan, Jiazheng Sun, Beilei Zeng, Tingxiu Xiang, Jinxiang Tan, Guosheng Ren, Yuanyuan Wang
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Cell Communication and Signaling
Subjects:
Adipocyte
Breast cancer
Crosstalk
ATGL
FABP5
Aggressiveness
Online Access:http://link.springer.com/article/10.1186/s12964-018-0221-6

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