Estradiol-treated female mice as surrogate hosts for Neisseria gonorrhoeae genital tract infections
Historically, animal modeling of gonorrhea has been hampered by the exclusive adaptation of Neisseria gonorrheae to humans. Genital tract infection can be established in female mice that are treated with 17β-estradiol, however, and many features of experimental murine infection mimic human infection...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2011-07-01
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| Series: | Frontiers in Cellular and Infection Microbiology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fmicb.2011.00107/full |