Effect of Tongmai Huoxue decoction combined with warm needling on hemorheology and antioxidant capacity in patients with high altitude polycythemia
Objective: To investigate the curative effect of Tongmai Huoxue Decoction combined with warm needling on the treatment of High altitude polycythemia (HAPC), and to analyze the changes of hemorheology and antioxidant ability before and after treatment. Methods: A total of 90 HAPC patients were ran...
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doaj-8f3d2e1d0f9b4fe989337c209e1829b92020-11-24T23:36:24ZengEditorial Board of Journal of Hainan Medical UniversityJournal of Hainan Medical University1007-12371007-12372017-08-0123151518Effect of Tongmai Huoxue decoction combined with warm needling on hemorheology and antioxidant capacity in patients with high altitude polycythemiaWen-Ling Zhao0Ru-Yi Yang1Chang-Xia Cao2Zhan-Fang Guo3Department of Integrated Traditional Chinese and Western Medicine, Affiliated Hospital of Qinghai University, Xining 810000, ChinaDepartment of Integrated Traditional Chinese and Western Medicine, Affiliated Hospital of Qinghai University, Xining 810000, ChinaDepartment of Integrated Traditional Chinese and Western Medicine, Affiliated Hospital of Qinghai University, Xining 810000, ChinaDepartment of Integrated Traditional Chinese and Western Medicine, Affiliated Hospital of Qinghai University, Xining 810000, ChinaObjective: To investigate the curative effect of Tongmai Huoxue Decoction combined with warm needling on the treatment of High altitude polycythemia (HAPC), and to analyze the changes of hemorheology and antioxidant ability before and after treatment. Methods: A total of 90 HAPC patients were randomly divided into control group and observation group. The control group was treated with low molecular weight dextran and captopril. On the basis of this, the observation group was supplemented with Tongmai Huoxue Decoction combined with warm needling. Hemorheology and antioxidant markers were measured before and after treatment in all subjects. Results: Before treatment, there were no significant differences in the hemorheology indexes between the control group and the observation group. After treatment, the two groups of hemorheology related indicators were significantly lower than those before treatment, including whole blood low shear reduction viscosity, whole blood high shear reduction viscosity, plasma viscosity, Hb, Hct and RBC. The levels of the observation group were significantly lower than that of the control group. Before treatment, there was no significant difference in antioxidant indexes between the control group and the observation group. After treatment, the levels of serum superoxide dismutase (SOD) and glutathione (GSH) in the two groups were higher than those in the pre-treatment, while the content of malondialdehyde (MDA) was lower than that before treatment. The levels of serum SOD and GSH in the observation group were higher than those in the control group, and the MDA content was lower than that in the control group. Conclusion: Routine treatment of Western medicine combined with Tongmai Huoxue Decoction joint warm needling method may reduce hemoglobin, improve hemorheology and improve antioxidant ability in HAPC patients, and it may be one of the potential effective drugs for adjuvant therapy of HAPC.http://www.hnykdxxb.com/PDF/201715/4.pdfTongmai Huoxue DecoctionHemorheologyAnti-oxidationWarm needlingHigh altitude polycythemia |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Wen-Ling Zhao Ru-Yi Yang Chang-Xia Cao Zhan-Fang Guo |
spellingShingle |
Wen-Ling Zhao Ru-Yi Yang Chang-Xia Cao Zhan-Fang Guo Effect of Tongmai Huoxue decoction combined with warm needling on hemorheology and antioxidant capacity in patients with high altitude polycythemia Journal of Hainan Medical University Tongmai Huoxue Decoction Hemorheology Anti-oxidation Warm needling High altitude polycythemia |
author_facet |
Wen-Ling Zhao Ru-Yi Yang Chang-Xia Cao Zhan-Fang Guo |
author_sort |
Wen-Ling Zhao |
title |
Effect of Tongmai Huoxue decoction combined with warm needling on hemorheology and antioxidant capacity in patients with high altitude polycythemia |
title_short |
Effect of Tongmai Huoxue decoction combined with warm needling on hemorheology and antioxidant capacity in patients with high altitude polycythemia |
title_full |
Effect of Tongmai Huoxue decoction combined with warm needling on hemorheology and antioxidant capacity in patients with high altitude polycythemia |
title_fullStr |
Effect of Tongmai Huoxue decoction combined with warm needling on hemorheology and antioxidant capacity in patients with high altitude polycythemia |
title_full_unstemmed |
Effect of Tongmai Huoxue decoction combined with warm needling on hemorheology and antioxidant capacity in patients with high altitude polycythemia |
title_sort |
effect of tongmai huoxue decoction combined with warm needling on hemorheology and antioxidant capacity in patients with high altitude polycythemia |
publisher |
Editorial Board of Journal of Hainan Medical University |
series |
Journal of Hainan Medical University |
issn |
1007-1237 1007-1237 |
publishDate |
2017-08-01 |
description |
Objective: To investigate the curative effect of Tongmai Huoxue Decoction combined with
warm needling on the treatment of High altitude polycythemia (HAPC), and to analyze the
changes of hemorheology and antioxidant ability before and after treatment. Methods: A
total of 90 HAPC patients were randomly divided into control group and observation group.
The control group was treated with low molecular weight dextran and captopril. On the basis
of this, the observation group was supplemented with Tongmai Huoxue Decoction combined
with warm needling. Hemorheology and antioxidant markers were measured before and after
treatment in all subjects. Results: Before treatment, there were no significant differences
in the hemorheology indexes between the control group and the observation group. After
treatment, the two groups of hemorheology related indicators were significantly lower than
those before treatment, including whole blood low shear reduction viscosity, whole blood high
shear reduction viscosity, plasma viscosity, Hb, Hct and RBC. The levels of the observation
group were significantly lower than that of the control group. Before treatment, there was no
significant difference in antioxidant indexes between the control group and the observation
group. After treatment, the levels of serum superoxide dismutase (SOD) and glutathione
(GSH) in the two groups were higher than those in the pre-treatment, while the content of
malondialdehyde (MDA) was lower than that before treatment. The levels of serum SOD
and GSH in the observation group were higher than those in the control group, and the MDA
content was lower than that in the control group. Conclusion: Routine treatment of Western
medicine combined with Tongmai Huoxue Decoction joint warm needling method may reduce
hemoglobin, improve hemorheology and improve antioxidant ability in HAPC patients, and it
may be one of the potential effective drugs for adjuvant therapy of HAPC. |
topic |
Tongmai Huoxue Decoction Hemorheology Anti-oxidation Warm needling High altitude polycythemia |
url |
http://www.hnykdxxb.com/PDF/201715/4.pdf |
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