Genital Tract Infections in an Isolated Community: 100 Women of the Príncipe Island
Objective. To characterize the vaginal microbiome and the rate of sexually transmitted infections (STIs) in the women of Príncipe (São Tomé and Príncipe). Methods. Cross-sectional study of 100 consecutive women, invited for a free appointment and cervical cancer screening. A vaginal slide (wet mount...
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Series: | Infectious Diseases in Obstetrics and Gynecology |
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doaj-8f461171c8214207ba9cb26d9be6c9d42020-11-24T22:55:09ZengHindawi LimitedInfectious Diseases in Obstetrics and Gynecology1064-74491098-09972017-01-01201710.1155/2017/30585693058569Genital Tract Infections in an Isolated Community: 100 Women of the Príncipe IslandPedro Vieira-Baptista0Svitrigaile Grinceviciene1Gert Bellen2Carlos Sousa3Conceição Saldanha4Davy Vanden Broeck5John-Paul Bogers6Gilbert Donders7Department of Gynecology and Obstetrics, Centro Hospitalar de São João, Porto, PortugalFemicare, Clinical Research for Women, Tienen, BelgiumFemicare, Clinical Research for Women, Tienen, BelgiumLaboratório de Anatomia Patológica (LAP), Unilabs, Porto, PortugalLaboratório de Anatomia Patológica (LAP), Unilabs, Porto, PortugalAlgemeen Medisch Laboratorium, Antwerp, BelgiumAlgemeen Medisch Laboratorium, Antwerp, BelgiumFemicare, Clinical Research for Women, Tienen, BelgiumObjective. To characterize the vaginal microbiome and the rate of sexually transmitted infections (STIs) in the women of Príncipe (São Tomé and Príncipe). Methods. Cross-sectional study of 100 consecutive women, invited for a free appointment and cervical cancer screening. A vaginal slide (wet mount microscopy) and a cervical sample (ThinPrep®) (Pap test, high risk human papillomavirus [HR-HPV], N. gonorrhea [NG], T. vaginalis [TV], and C. trachomatis [CT]) were obtained. Results. TV, NG, CT, and HIV were found in 8.0%, 2.0%, 3.0%, and 2.0%, respectively, and were more prevalent in younger women. HR-HPV was positive in 36.7%; 2 were positive for HPV18, but none for HPV16. Coinfection of HPV with other STIs was 8.3%. Prevalence of abnormal vaginal flora (AVF) was 82.5%, mostly bacterial vaginosis (BV) 54.6%, and moderate/severe aerobic vaginitis (msAV) 25.8%. HR-HPV was not related to BV (p=0.67). The association of abnormal Pap test with msAV was not significant (p=0.08). Conclusion. The prevalence of NG, CT, TV, and HR-HPV was according to expected, while that of HR-AVF was higher. The surprisingly low prevalence of HPV16 and HPV18 must be considered in the design of programs for prevention and vaccination; this setting can be useful as a model for postvaccination scenarios.http://dx.doi.org/10.1155/2017/3058569 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Pedro Vieira-Baptista Svitrigaile Grinceviciene Gert Bellen Carlos Sousa Conceição Saldanha Davy Vanden Broeck John-Paul Bogers Gilbert Donders |
spellingShingle |
Pedro Vieira-Baptista Svitrigaile Grinceviciene Gert Bellen Carlos Sousa Conceição Saldanha Davy Vanden Broeck John-Paul Bogers Gilbert Donders Genital Tract Infections in an Isolated Community: 100 Women of the Príncipe Island Infectious Diseases in Obstetrics and Gynecology |
author_facet |
Pedro Vieira-Baptista Svitrigaile Grinceviciene Gert Bellen Carlos Sousa Conceição Saldanha Davy Vanden Broeck John-Paul Bogers Gilbert Donders |
author_sort |
Pedro Vieira-Baptista |
title |
Genital Tract Infections in an Isolated Community: 100 Women of the Príncipe Island |
title_short |
Genital Tract Infections in an Isolated Community: 100 Women of the Príncipe Island |
title_full |
Genital Tract Infections in an Isolated Community: 100 Women of the Príncipe Island |
title_fullStr |
Genital Tract Infections in an Isolated Community: 100 Women of the Príncipe Island |
title_full_unstemmed |
Genital Tract Infections in an Isolated Community: 100 Women of the Príncipe Island |
title_sort |
genital tract infections in an isolated community: 100 women of the príncipe island |
publisher |
Hindawi Limited |
series |
Infectious Diseases in Obstetrics and Gynecology |
issn |
1064-7449 1098-0997 |
publishDate |
2017-01-01 |
description |
Objective. To characterize the vaginal microbiome and the rate of sexually transmitted infections (STIs) in the women of Príncipe (São Tomé and Príncipe). Methods. Cross-sectional study of 100 consecutive women, invited for a free appointment and cervical cancer screening. A vaginal slide (wet mount microscopy) and a cervical sample (ThinPrep®) (Pap test, high risk human papillomavirus [HR-HPV], N. gonorrhea [NG], T. vaginalis [TV], and C. trachomatis [CT]) were obtained. Results. TV, NG, CT, and HIV were found in 8.0%, 2.0%, 3.0%, and 2.0%, respectively, and were more prevalent in younger women. HR-HPV was positive in 36.7%; 2 were positive for HPV18, but none for HPV16. Coinfection of HPV with other STIs was 8.3%. Prevalence of abnormal vaginal flora (AVF) was 82.5%, mostly bacterial vaginosis (BV) 54.6%, and moderate/severe aerobic vaginitis (msAV) 25.8%. HR-HPV was not related to BV (p=0.67). The association of abnormal Pap test with msAV was not significant (p=0.08). Conclusion. The prevalence of NG, CT, TV, and HR-HPV was according to expected, while that of HR-AVF was higher. The surprisingly low prevalence of HPV16 and HPV18 must be considered in the design of programs for prevention and vaccination; this setting can be useful as a model for postvaccination scenarios. |
url |
http://dx.doi.org/10.1155/2017/3058569 |
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