Aberrant Regulation of mRNA m6A Modification in Cancer Development

Aberrant Regulation of mRNA m6A Modification in Cancer Development

N6-methyladenosine (m6A) is the most prevalent internal modification of eukaryotic messenger RNAs (mRNAs). The m6A modification in RNA can be catalyzed by methyltransferases, or removed by demethylases, which are termed m6A writers and erasers, respectively. Selective recognition and binding by dist...

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Bibliographic Details
Main Authors: Junyun Luo, Hui Liu, Siyu Luan, Chongsheng He, Zhaoyong Li
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:International Journal of Molecular Sciences
Subjects:
m6A
m6A writer
m6A eraser
m6A reader
cancer development
Online Access:http://www.mdpi.com/1422-0067/19/9/2515

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