Optical investigations reveal the effects of 2-aminoethyldiphenyl borate on STIM1 puncta formation

Optical investigations reveal the effects of 2-aminoethyldiphenyl borate on STIM1 puncta formation

2-Aminoethyldiphenyl borate (2-APB) is the most commonly used pharmacological agent in the study of calcium release-activated channels (CRACs); however, its inhibitory mechanism to CRACs remains unclear. To address this issue, we systematically employed confocal imaging, dual-wavelength excitation p...

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Bibliographic Details
Main Authors: Tao Yu, Shangbin Chen, Jingying Pan, Conglin Su, Jun He
Format: Article
Language:English
Published: World Scientific Publishing 2018-03-01
Series:Journal of Innovative Optical Health Sciences
Subjects:
SOCE
CRAC
2-aminoethyldiphenyl borate
STIM1
Orai1
confocal imaging
FRET
Online Access:http://www.worldscientific.com/doi/pdf/10.1142/S1793545818500037

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