CHOICE OF TARGETED DRUG FOR SECOND-LINE METASTATIC COLON CANCER CHEMOTHERAPY

During the last 5 years the prognosis of metastatic colorectal cancer patients improved significantly. This results not only from increased amount of surgery for metastatic disease and use of targeted drugs in first-line treatment, but also from increased number of patients receiving effective secon...

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Bibliographic Details
Main Authors: M. Yu. Fedyanin, A. A. Tryakin, S. A. Tjulandin
Format: Article
Language:Russian
Published: “ABV-press” Publishing house”, LLC 2015-05-01
Series:Тазовая хирургия и онкология
Subjects:
Online Access:https://ok.abvpress.ru/jour/article/view/123
Description
Summary:During the last 5 years the prognosis of metastatic colorectal cancer patients improved significantly. This results not only from increased amount of surgery for metastatic disease and use of targeted drugs in first-line treatment, but also from increased number of patients receiving effective second- and third-line chemotherapy. Currently a minimum of 7 treatment groups can be distinguished depending on prior first-line chemo- and targeted therapy. Consequentially we have less evidence-based data to guide the treatment choice for next treatment lines. This article discusses the choice of targeted drugs in combination with second-line chemotherapy.
ISSN:2686-9594