Inverse association between physical activity and blood glucose is independent of sex, menopause status and first‐degree family history of diabetes
Abstract Aims/Introduction Exercise training is a recognized strategy central to the prevention, treatment, and management of diabetes and prediabetes. The aim of the present study was to investigate the association between physical activity and blood glucose, as well as the influence of sex, menopa...
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doaj-8f6a0651cae14594bded0c78b5faee222021-05-02T20:20:42ZengWileyJournal of Diabetes Investigation2040-11162040-11242019-11-011061502150910.1111/jdi.13062Inverse association between physical activity and blood glucose is independent of sex, menopause status and first‐degree family history of diabetesXiang Hu0Weihui Yu1Lijuan Yang2Wei Pan3Qiya Si4Xueqin Chen5Qianqian Li6Xuejiang Gu7Department of Endocrine and Metabolic Diseases the First Affiliated Hospital of Wenzhou Medical University Wenzhou Zhejiang ChinaDepartment of Endocrine and Metabolic Diseases the First Affiliated Hospital of Wenzhou Medical University Wenzhou Zhejiang ChinaDepartment of Endocrine and Metabolic Diseases the First Affiliated Hospital of Wenzhou Medical University Wenzhou Zhejiang ChinaDepartment of Endocrine and Metabolic Diseases the First Affiliated Hospital of Wenzhou Medical University Wenzhou Zhejiang ChinaDepartment of Endocrine and Metabolic Diseases the First Affiliated Hospital of Wenzhou Medical University Wenzhou Zhejiang ChinaDepartment of Endocrine and Metabolic Diseases the First Affiliated Hospital of Wenzhou Medical University Wenzhou Zhejiang ChinaDepartment of Endocrine and Metabolic Diseases the First Affiliated Hospital of Wenzhou Medical University Wenzhou Zhejiang ChinaDepartment of Endocrine and Metabolic Diseases the First Affiliated Hospital of Wenzhou Medical University Wenzhou Zhejiang ChinaAbstract Aims/Introduction Exercise training is a recognized strategy central to the prevention, treatment, and management of diabetes and prediabetes. The aim of the present study was to investigate the association between physical activity and blood glucose, as well as the influence of sex, menopause status and family history of diabetes. Materials and Methods Participants with normal weight were selected from Risk Evaluation of Cancers in Chinese Diabetic Individuals: A Longitudinal Study, and divided into inactive (moderate‐to‐vigorous‐intensity physical activity [MVPA] <30 min/week), low‐degree (MVPA ≥30 and ≤420 min/week) and high‐degree (MVPA >420 min/week) activity groups. Results A total of 2,601 individuals with an average age of 57.85 ± 8.39 years were enrolled. Multivariate anova uncovered that after adjustment for sex and menopause status, and family history of diabetes, respectively, fasting plasma glucose, 2‐h plasma glucose and glycated hemoglobin A1c decreased through inactive, low‐degree and high‐degree activity groups (all P for trend <0.05). The association of blood glucose indexes with physical activity was independent of this association with sex and menopause status, and first‐degree family history of diabetes, respectively. Multivariate linear regression analyses showed that MVPA was an independent factor associated negatively with fasting plasma glucose, 2‐h plasma glucose and glycated hemoglobin A1c, respectively (all P < 0.01). Conclusions A higher degree of physical activity was associated with lower blood glucose regardless of sex, menopause status and first‐degree family history of diabetes. MVPA is a negative factor associated with blood glucose independently. Physical activity of adequate duration and intensity is strongly recommended to individuals with susceptibility to diabetes as a result of sex and family history, but without overweight/obesity.https://doi.org/10.1111/jdi.13062Moderate‐to‐vigorous‐intensity physical activityPlasma glucoseSex difference |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Xiang Hu Weihui Yu Lijuan Yang Wei Pan Qiya Si Xueqin Chen Qianqian Li Xuejiang Gu |
spellingShingle |
Xiang Hu Weihui Yu Lijuan Yang Wei Pan Qiya Si Xueqin Chen Qianqian Li Xuejiang Gu Inverse association between physical activity and blood glucose is independent of sex, menopause status and first‐degree family history of diabetes Journal of Diabetes Investigation Moderate‐to‐vigorous‐intensity physical activity Plasma glucose Sex difference |
author_facet |
Xiang Hu Weihui Yu Lijuan Yang Wei Pan Qiya Si Xueqin Chen Qianqian Li Xuejiang Gu |
author_sort |
Xiang Hu |
title |
Inverse association between physical activity and blood glucose is independent of sex, menopause status and first‐degree family history of diabetes |
title_short |
Inverse association between physical activity and blood glucose is independent of sex, menopause status and first‐degree family history of diabetes |
title_full |
Inverse association between physical activity and blood glucose is independent of sex, menopause status and first‐degree family history of diabetes |
title_fullStr |
Inverse association between physical activity and blood glucose is independent of sex, menopause status and first‐degree family history of diabetes |
title_full_unstemmed |
Inverse association between physical activity and blood glucose is independent of sex, menopause status and first‐degree family history of diabetes |
title_sort |
inverse association between physical activity and blood glucose is independent of sex, menopause status and first‐degree family history of diabetes |
publisher |
Wiley |
series |
Journal of Diabetes Investigation |
issn |
2040-1116 2040-1124 |
publishDate |
2019-11-01 |
description |
Abstract Aims/Introduction Exercise training is a recognized strategy central to the prevention, treatment, and management of diabetes and prediabetes. The aim of the present study was to investigate the association between physical activity and blood glucose, as well as the influence of sex, menopause status and family history of diabetes. Materials and Methods Participants with normal weight were selected from Risk Evaluation of Cancers in Chinese Diabetic Individuals: A Longitudinal Study, and divided into inactive (moderate‐to‐vigorous‐intensity physical activity [MVPA] <30 min/week), low‐degree (MVPA ≥30 and ≤420 min/week) and high‐degree (MVPA >420 min/week) activity groups. Results A total of 2,601 individuals with an average age of 57.85 ± 8.39 years were enrolled. Multivariate anova uncovered that after adjustment for sex and menopause status, and family history of diabetes, respectively, fasting plasma glucose, 2‐h plasma glucose and glycated hemoglobin A1c decreased through inactive, low‐degree and high‐degree activity groups (all P for trend <0.05). The association of blood glucose indexes with physical activity was independent of this association with sex and menopause status, and first‐degree family history of diabetes, respectively. Multivariate linear regression analyses showed that MVPA was an independent factor associated negatively with fasting plasma glucose, 2‐h plasma glucose and glycated hemoglobin A1c, respectively (all P < 0.01). Conclusions A higher degree of physical activity was associated with lower blood glucose regardless of sex, menopause status and first‐degree family history of diabetes. MVPA is a negative factor associated with blood glucose independently. Physical activity of adequate duration and intensity is strongly recommended to individuals with susceptibility to diabetes as a result of sex and family history, but without overweight/obesity. |
topic |
Moderate‐to‐vigorous‐intensity physical activity Plasma glucose Sex difference |
url |
https://doi.org/10.1111/jdi.13062 |
work_keys_str_mv |
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