IRF4 Mediates the Oncogenic Effects of STAT3 in Anaplastic Large Cell Lymphomas

IRF4 Mediates the Oncogenic Effects of STAT3 in Anaplastic Large Cell Lymphomas

Systemic anaplastic large cell lymphomas (ALCL) are a category of T-cell non-Hodgkin’s lymphomas which can be divided into anaplastic lymphoma kinase (ALK) positive and ALK negative subgroups, based on ALK gene rearrangements. Among several pathways aberrantly activated in ALCL, the constitutive act...

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Bibliographic Details
Main Authors: Cecilia Bandini, Aldi Pupuleku, Elisa Spaccarotella, Elisa Pellegrino, Rui Wang, Nicoletta Vitale, Carlotta Duval, Daniela Cantarella, Andrea Rinaldi, Paolo Provero, Ferdinando Di Cunto, Enzo Medico, Francesco Bertoni, Giorgio Inghirami, Roberto Piva
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:Cancers
Subjects:
anaplastic large cell lymphomas
ALK
STAT3
IRF4
immunomodulatory drugs
JQ1
Online Access:http://www.mdpi.com/2072-6694/10/1/21

Internet

http://www.mdpi.com/2072-6694/10/1/21

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