Molecular Insights into Poly(ADP-ribose) Recognition and Processing

Molecular Insights into Poly(ADP-ribose) Recognition and Processing

Poly(ADP-ribosyl)ation is a post-translational protein modification involved in the regulation of important cellular functions including DNA repair, transcription, mitosis and apoptosis. The amount of poly(ADP-ribosyl)ation (PAR) in cells reflects the balance of synthesis, mediated by the PARP prote...

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Bibliographic Details
Main Authors: Ivan Ahel, Eva Barkauskaite, Roko Žaja, Andreja Mikoč
Format: Article
Language:English
Published: MDPI AG 2012-12-01
Series:Biomolecules
Subjects:
Poly(ADP-ribose)
PARP
PARG
macrodomain
protein modification
Online Access:http://www.mdpi.com/2218-273X/3/1/1

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