First-line palliative systemic therapy alternated with electrostatic pressurised intraperitoneal aerosol chemotherapy (oxaliplatin) for isolated unresectable colorectal peritoneal metastases: protocol of a multicentre, single-arm, phase II study (CRC-PIPAC-II)

First-line palliative systemic therapy alternated with electrostatic pressurised intraperitoneal aerosol chemotherapy (oxaliplatin) for isolated unresectable colorectal peritoneal metastases: protocol of a multicentre, single-arm, phase II study (CRC-PIPAC-II)

Introduction Despite its increasing use, first-line palliative systemic therapy alternated with electrostatic pressurised intraperitoneal aerosol chemotherapy with oxaliplatin (ePIPAC-OX), hereinafter referred to as first-line bidirectional therapy, has never been prospectively investigated in patie...

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Main Authors: Joost Nederend, Alexander Constantinides, Onno Kranenburg, Maartje Los, Djamila Boerma, Marinus J. Wiezer, Robin J. Lurvink, Paulien Rauwerdink, Koen P. Rovers, Emma C.E. Wassenaar, Maarten J. Deenen, Clément J.R. Huysentruyt, Iris van 't Erve, Remond J.A. Fijneman, Erik J.R.J. van der Hoeven, Cornelis A. Seldenrijk, Karin H. Herbschleb, Anna M.J. Thijs, Geert-Jan M. Creemers, Jacobus W.A. Burger, Simon W. Nienhuijs, Ignace H.J.T. de Hingh
Format: Article
Language:English
Published: BMJ Publishing Group 2021-03-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/11/3/e044811.full

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https://bmjopen.bmj.com/content/11/3/e044811.full

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