Decreased CREB levels suppress epilepsy
Epilepsy is a common neurologic disorder yet no treatments aimed at preventing epilepsy have been developed. Several molecules including genes containing cAMP response elements (CREs) in their promoters have been identified that contribute to the development of epilepsy, a process called epileptogen...
Main Authors: | Xinjian Zhu, Xiao Han, Julie A. Blendy, Brenda E. Porter |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2012-01-01
|
Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996111002634 |
Similar Items
-
Upregulation of CREM/ICER suppresses wound endothelial CRE-HIF-1α-VEGF-dependent signaling and impairs angiogenesis in type 2 diabetes
by: Milad S. Bitar, et al.
Published: (2015-01-01) -
Calcium-independent phospholipase A2 mediates CREB phosphorylation in double-stranded RNA-stimulated endothelial cells
by: Bradley D. Martinson, et al.
Published: (2003-09-01) -
The role of hepatic transcription factor cAMP response element-binding protein (CREB) during the development of experimental nonalcoholic fatty liver: a biochemical and histomorphometric study
by: Ashraf K. Awaad, et al.
Published: (2020-07-01) -
Silencing of ICERs (Inducible cAMP Early Repressors) results in partial protection of neurons from programmed cell death
by: Katarzyna Bieganska, et al.
Published: (2012-02-01) -
GIP increases human adipocyte LPL expression through CREB and TORC2-mediated trans-activation of the LPL gene
by: Su-Jin Kim, et al.
Published: (2010-11-01)