An analysis of extensible modelling for functional genomics data
<p>Abstract</p> <p>Background</p> <p>Several data formats have been developed for large scale biological experiments, using a variety of methodologies. Most data formats contain a <monospace>mechanism</monospace> for allowing extensions to encode unanticipat...
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doaj-8fa8ba6d4a9f497d89ad0e3c9922877a2020-11-24T21:06:12ZengBMCBMC Bioinformatics1471-21052005-09-016123510.1186/1471-2105-6-235An analysis of extensible modelling for functional genomics dataPaton Norman WJones Andrew R<p>Abstract</p> <p>Background</p> <p>Several data formats have been developed for large scale biological experiments, using a variety of methodologies. Most data formats contain a <monospace>mechanism</monospace> for allowing extensions to encode unanticipated data types. Extensions to data formats are important because the experimental methodologies tend to be fairly diverse and rapidly evolving, which hinders the creation of formats that will be stable over time.</p> <p>Results</p> <p>In this paper we review the data formats that exist in functional genomics, some of which have become <it>de facto </it>or <it>de jure </it>standards, with a particular focus on how each domain has been modelled, and how each format allows extensions. We describe the tasks that are frequently performed over data formats and analyse how well each task is supported by a particular modelling structure.</p> <p>Conclusion</p> <p>From our analysis, we make recommendations as to the types of modelling structure that are most suitable for particular types of experimental annotation. There are several standards currently under development that we believe could benefit from systematically following a set of guidelines.</p> http://www.biomedcentral.com/1471-2105/6/235 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Paton Norman W Jones Andrew R |
spellingShingle |
Paton Norman W Jones Andrew R An analysis of extensible modelling for functional genomics data BMC Bioinformatics |
author_facet |
Paton Norman W Jones Andrew R |
author_sort |
Paton Norman W |
title |
An analysis of extensible modelling for functional genomics data |
title_short |
An analysis of extensible modelling for functional genomics data |
title_full |
An analysis of extensible modelling for functional genomics data |
title_fullStr |
An analysis of extensible modelling for functional genomics data |
title_full_unstemmed |
An analysis of extensible modelling for functional genomics data |
title_sort |
analysis of extensible modelling for functional genomics data |
publisher |
BMC |
series |
BMC Bioinformatics |
issn |
1471-2105 |
publishDate |
2005-09-01 |
description |
<p>Abstract</p> <p>Background</p> <p>Several data formats have been developed for large scale biological experiments, using a variety of methodologies. Most data formats contain a <monospace>mechanism</monospace> for allowing extensions to encode unanticipated data types. Extensions to data formats are important because the experimental methodologies tend to be fairly diverse and rapidly evolving, which hinders the creation of formats that will be stable over time.</p> <p>Results</p> <p>In this paper we review the data formats that exist in functional genomics, some of which have become <it>de facto </it>or <it>de jure </it>standards, with a particular focus on how each domain has been modelled, and how each format allows extensions. We describe the tasks that are frequently performed over data formats and analyse how well each task is supported by a particular modelling structure.</p> <p>Conclusion</p> <p>From our analysis, we make recommendations as to the types of modelling structure that are most suitable for particular types of experimental annotation. There are several standards currently under development that we believe could benefit from systematically following a set of guidelines.</p> |
url |
http://www.biomedcentral.com/1471-2105/6/235 |
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