Two monoclonal antibodies against glycoprotein Gn protect mice from Rift Valley Fever challenge by cooperative effects.
Rift Valley fever virus (RVFV) is a zoonotic arbovirus that causes severe disease in humans and ruminants. The infection is characterized by abortions in pregnant animals, high mortality in neonates as well as febrile illness in humans that develop in 1% of cases encephalitis or hemorrhagic fever. T...
Main Authors: | Benjamin Gutjahr, Markus Keller, Melanie Rissmann, Felicitas von Arnim, Susanne Jäckel, Sven Reiche, Reiner Ulrich, Martin H Groschup, Martin Eiden |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020-03-01
|
Series: | PLoS Neglected Tropical Diseases |
Online Access: | https://doi.org/10.1371/journal.pntd.0008143 |
Similar Items
-
Vaccine Efficacy of Self-Assembled Multimeric Protein Scaffold Particles Displaying the Glycoprotein Gn Head Domain of Rift Valley Fever Virus
by: Paul J. Wichgers Schreur, et al.
Published: (2021-03-01) -
Competency of Amphibians and Reptiles and Their Potential Role as Reservoir Hosts for Rift Valley Fever Virus
by: Melanie Rissmann, et al.
Published: (2020-10-01) -
Productive Propagation of Rift Valley Fever Phlebovirus Vaccine Strain MP-12 in<em> Rousettus aegyptiacus</em> Fruit Bats
by: Anne Balkema-Buschmann, et al.
Published: (2018-11-01) -
Replication of Rift Valley Fever Virus in Amphibian and Reptile-Derived Cell Lines
by: Melanie Rissmann, et al.
Published: (2021-05-01) -
Study of the surface glycoprotein of Rift Valley fever virus using monoclonal antibodies
by: Besselaar, Terry Gail
Published: (2016)