Splenic rupture as the presenting manifestation of primary splenic angiosarcoma in a teenage woman: a case report
<p>Abstract</p> <p>Introduction</p> <p>Primary splenic angiosarcoma is a rare neoplasm of vascular origin carrying a very poor prognosis, partly due to its high metastatic potential. This disease presents frequently with splenic rupture and hemorrhage. We report the cas...
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doaj-8fb5e5fd5fca4589b1c20b627e0211332020-11-24T20:48:01ZengBMCJournal of Medical Case Reports1752-19472008-04-012113310.1186/1752-1947-2-133Splenic rupture as the presenting manifestation of primary splenic angiosarcoma in a teenage woman: a case reportManouras AndreasGiannopoulos PanagiotisToufektzian LevonMarkogiannakis HaridimosLagoudianakis Emmanuel EPapadima ArtemisiaPapanikolaou DimitriosFilis KonstantinosKekis Panagiotis<p>Abstract</p> <p>Introduction</p> <p>Primary splenic angiosarcoma is a rare neoplasm of vascular origin carrying a very poor prognosis, partly due to its high metastatic potential. This disease presents frequently with splenic rupture and hemorrhage. We report the case of a 17-year-old woman who presented with rupture of a primary splenic angiosarcoma.</p> <p>Case presentation</p> <p>The patient presented with diffuse abdominal pain and distention. Clinical examination revealed severe tenderness in the left upper abdominal quadrant, a palpable abdominal mass, and hemodynamic instability with a systolic arterial blood pressure of 75 mmHg and heart rate of 135 beats per minute. Blood tests revealed anemia (hemoglobin 7.0 g/dl) and thrombocytopenia (platelets 70 × 10<sup>9</sup>/liter). After initial fluid resuscitation and stabilization, abdominal ultrasound and computed tomography were performed, revealing a large quantity of intraperitoneal free fluid, an enlarged spleen, and a heterogeneous low-density signal within the splenic parenchyma, which showed varying degrees of contrast enhancement. At laparotomy a huge (weight 1530 g, diameter 19 cm) actively bleeding spleen was identified and splenectomy was performed. Histopathology showed a primary splenic angiosarcoma. After an uneventful recovery, the patient was discharged on the sixth postoperative day.</p> <p>Conclusion</p> <p>Primary splenic angiosarcoma is rare. Although this malignancy is usually encountered in advanced age, there have been a few reported cases among younger patients. The case reported here presented with splenic rupture, was treated by laparotomy and splenectomy, and the patient is disease free 16 months after surgery.</p> http://www.jmedicalcasereports.com/content/2/1/133 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Manouras Andreas Giannopoulos Panagiotis Toufektzian Levon Markogiannakis Haridimos Lagoudianakis Emmanuel E Papadima Artemisia Papanikolaou Dimitrios Filis Konstantinos Kekis Panagiotis |
spellingShingle |
Manouras Andreas Giannopoulos Panagiotis Toufektzian Levon Markogiannakis Haridimos Lagoudianakis Emmanuel E Papadima Artemisia Papanikolaou Dimitrios Filis Konstantinos Kekis Panagiotis Splenic rupture as the presenting manifestation of primary splenic angiosarcoma in a teenage woman: a case report Journal of Medical Case Reports |
author_facet |
Manouras Andreas Giannopoulos Panagiotis Toufektzian Levon Markogiannakis Haridimos Lagoudianakis Emmanuel E Papadima Artemisia Papanikolaou Dimitrios Filis Konstantinos Kekis Panagiotis |
author_sort |
Manouras Andreas |
title |
Splenic rupture as the presenting manifestation of primary splenic angiosarcoma in a teenage woman: a case report |
title_short |
Splenic rupture as the presenting manifestation of primary splenic angiosarcoma in a teenage woman: a case report |
title_full |
Splenic rupture as the presenting manifestation of primary splenic angiosarcoma in a teenage woman: a case report |
title_fullStr |
Splenic rupture as the presenting manifestation of primary splenic angiosarcoma in a teenage woman: a case report |
title_full_unstemmed |
Splenic rupture as the presenting manifestation of primary splenic angiosarcoma in a teenage woman: a case report |
title_sort |
splenic rupture as the presenting manifestation of primary splenic angiosarcoma in a teenage woman: a case report |
publisher |
BMC |
series |
Journal of Medical Case Reports |
issn |
1752-1947 |
publishDate |
2008-04-01 |
description |
<p>Abstract</p> <p>Introduction</p> <p>Primary splenic angiosarcoma is a rare neoplasm of vascular origin carrying a very poor prognosis, partly due to its high metastatic potential. This disease presents frequently with splenic rupture and hemorrhage. We report the case of a 17-year-old woman who presented with rupture of a primary splenic angiosarcoma.</p> <p>Case presentation</p> <p>The patient presented with diffuse abdominal pain and distention. Clinical examination revealed severe tenderness in the left upper abdominal quadrant, a palpable abdominal mass, and hemodynamic instability with a systolic arterial blood pressure of 75 mmHg and heart rate of 135 beats per minute. Blood tests revealed anemia (hemoglobin 7.0 g/dl) and thrombocytopenia (platelets 70 × 10<sup>9</sup>/liter). After initial fluid resuscitation and stabilization, abdominal ultrasound and computed tomography were performed, revealing a large quantity of intraperitoneal free fluid, an enlarged spleen, and a heterogeneous low-density signal within the splenic parenchyma, which showed varying degrees of contrast enhancement. At laparotomy a huge (weight 1530 g, diameter 19 cm) actively bleeding spleen was identified and splenectomy was performed. Histopathology showed a primary splenic angiosarcoma. After an uneventful recovery, the patient was discharged on the sixth postoperative day.</p> <p>Conclusion</p> <p>Primary splenic angiosarcoma is rare. Although this malignancy is usually encountered in advanced age, there have been a few reported cases among younger patients. The case reported here presented with splenic rupture, was treated by laparotomy and splenectomy, and the patient is disease free 16 months after surgery.</p> |
url |
http://www.jmedicalcasereports.com/content/2/1/133 |
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