Whole-genome sequencing for an enhanced understanding of genetic variation among South Africans
African populations show a high level of genetic diversity and extensive regional admixture. Here, the authors sequence the whole genomes of 24 South African individuals of different ethnolinguistic origin and find substantive genomic divergence between two southeastern Bantu-speaking groups.
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Nature Publishing Group
2017-12-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-017-00663-9 |
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doaj-8fda92929c8c49e5a1b6b54ed223b65f2021-05-11T07:22:07ZengNature Publishing GroupNature Communications2041-17232017-12-018111210.1038/s41467-017-00663-9Whole-genome sequencing for an enhanced understanding of genetic variation among South AfricansAnanyo Choudhury0Michèle Ramsay1Scott Hazelhurst2Shaun Aron3Soraya Bardien4Gerrit Botha5Emile R. Chimusa6Alan Christoffels7Junaid Gamieldien8Mahjoubeh J. Sefid-Dashti9Fourie Joubert10Ayton Meintjes11Nicola Mulder12Raj Ramesar13Jasper Rees14Kathrine Scholtz15Dhriti Sengupta16Himla Soodyall17Philip Venter18Louise Warnich19Michael S. Pepper20Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the WitwatersrandSydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the WitwatersrandSydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the WitwatersrandSydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the WitwatersrandDivision of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch UniversityComputational Biology Division, Department of Integrative Biomedical Sciences, IDM, University of Cape TownDivision of Human Genetics, Department of Pathology, IDM, Faculty of Health Sciences, University of Cape TownSouth African MRC Bioinformatics Unit, South African National Bioinformatics Institute, University of the Western CapeSouth African MRC Bioinformatics Unit, South African National Bioinformatics Institute, University of the Western CapeSouth African MRC Bioinformatics Unit, South African National Bioinformatics Institute, University of the Western CapeDepartment of Biochemistry and Genomics Research Institute, Centre for Bioinformatics and Computational Biology, University of PretoriaComputational Biology Division, Department of Integrative Biomedical Sciences, IDM, University of Cape TownComputational Biology Division, Department of Integrative Biomedical Sciences, IDM, University of Cape TownDivision of Human Genetics, Department of Pathology, IDM, Faculty of Health Sciences, University of Cape TownAgricultural Research CouncilDepartment of Preclinical Sciences, School of Health Care Sciences, Faculty of Health Sciences, University of LimpopoSydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the WitwatersrandDivision of Human Genetics, School of Pathology, Faculty of Health Sciences, University of the WitwatersrandDepartment of Medical Sciences, School of Health Sciences, Faculty of Health Sciences, University of LimpopoDepartment of Genetics, Stellenbosch UniversityInstitute for Cellular and Molecular Medicine, Department of Immunology, Faculty of Health Sciences, University of PretoriaAfrican populations show a high level of genetic diversity and extensive regional admixture. Here, the authors sequence the whole genomes of 24 South African individuals of different ethnolinguistic origin and find substantive genomic divergence between two southeastern Bantu-speaking groups.https://doi.org/10.1038/s41467-017-00663-9 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Ananyo Choudhury Michèle Ramsay Scott Hazelhurst Shaun Aron Soraya Bardien Gerrit Botha Emile R. Chimusa Alan Christoffels Junaid Gamieldien Mahjoubeh J. Sefid-Dashti Fourie Joubert Ayton Meintjes Nicola Mulder Raj Ramesar Jasper Rees Kathrine Scholtz Dhriti Sengupta Himla Soodyall Philip Venter Louise Warnich Michael S. Pepper |
| spellingShingle |
Ananyo Choudhury Michèle Ramsay Scott Hazelhurst Shaun Aron Soraya Bardien Gerrit Botha Emile R. Chimusa Alan Christoffels Junaid Gamieldien Mahjoubeh J. Sefid-Dashti Fourie Joubert Ayton Meintjes Nicola Mulder Raj Ramesar Jasper Rees Kathrine Scholtz Dhriti Sengupta Himla Soodyall Philip Venter Louise Warnich Michael S. Pepper Whole-genome sequencing for an enhanced understanding of genetic variation among South Africans Nature Communications |
| author_facet |
Ananyo Choudhury Michèle Ramsay Scott Hazelhurst Shaun Aron Soraya Bardien Gerrit Botha Emile R. Chimusa Alan Christoffels Junaid Gamieldien Mahjoubeh J. Sefid-Dashti Fourie Joubert Ayton Meintjes Nicola Mulder Raj Ramesar Jasper Rees Kathrine Scholtz Dhriti Sengupta Himla Soodyall Philip Venter Louise Warnich Michael S. Pepper |
| author_sort |
Ananyo Choudhury |
| title |
Whole-genome sequencing for an enhanced understanding of genetic variation among South Africans |
| title_short |
Whole-genome sequencing for an enhanced understanding of genetic variation among South Africans |
| title_full |
Whole-genome sequencing for an enhanced understanding of genetic variation among South Africans |
| title_fullStr |
Whole-genome sequencing for an enhanced understanding of genetic variation among South Africans |
| title_full_unstemmed |
Whole-genome sequencing for an enhanced understanding of genetic variation among South Africans |
| title_sort |
whole-genome sequencing for an enhanced understanding of genetic variation among south africans |
| publisher |
Nature Publishing Group |
| series |
Nature Communications |
| issn |
2041-1723 |
| publishDate |
2017-12-01 |
| description |
African populations show a high level of genetic diversity and extensive regional admixture. Here, the authors sequence the whole genomes of 24 South African individuals of different ethnolinguistic origin and find substantive genomic divergence between two southeastern Bantu-speaking groups. |
| url |
https://doi.org/10.1038/s41467-017-00663-9 |
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