The effect of cardiovascular diseases on the course of multiple sclerosis (review of literature)

• Main Authors: N. A. Neofidov, N. A. Totolyan, M. V. Shumilina, A. A. Skoromets, E. P. Evdoshenko
• Format: Article
• Language: Russian
• Published: Academician I.P. Pavlov First St. Petersburg State Medical University 2020-02-01
• Series: Učenye Zapiski Sankt-Peterburgskogo Gosudarstvennogo Medicinskogo Universiteta im. Akad. I.P. Pavlova
• Subjects: multiple sclerosis; comorbidity; vascular comorbidity; hypertension; stroke; chronic heart failure; ischemic heart disease; myocardial infarction; dyslipidemia; obesity
• Online Access: https://www.sci-notes.ru/jour/article/view/613

Comorbidity is one of the factors determining the course of multiple sclerosis. Cardiovascular pathology is one of the most common in the population as a whole, especially in age groups over 50. Several studies showed that arterial hypotension and dyslipidemia affected the course, progression rate, and neuroimaging characteristics of patients with multiple sclerosis. An important issue is the effect of disease modifying therapy on the course of concomitant diseases in patients with multiple sclerosis and the effect of concomitant diseases on the effectiveness and safety of disease modifying therapy. The question of the use of statins in multiple sclerosis remains controversial. This review presents data on vascular comorbidity in multiple sclerosis, including the prevalence of risk factors for cardiovascular pathology and concomitant vascular diseases in the population of patients with multiple sclerosis. Data on the effect of cardiovascular pathology on the course and treatment of multiple sclerosis were also analyzed.