Collective motion of cells crawling on a substrate: roles of cell shape and contact inhibition

Abstract Contact inhibition plays a crucial role in cell motility, wound healing, and tumour formation. By mimicking the mechanical motion of cells crawling on a substrate, we constructed a minimal model of migrating cells that naturally gives rise to contact inhibition of locomotion (CIL). The mode...

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Bibliographic Details
Main Authors: Simon K. Schnyder, John J. Molina, Yuki Tanaka, Ryoichi Yamamoto
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-05321-0