Effect of adjuvant therapy of transfer factor oral solution on the infection process of children with Mycoplasma pneumonia

• Main Author: Xuan Zhou
• Format: Article
• Language: English
• Published: Editorial Board of Journal of Hainan Medical University 2018-07-01
• Series: Journal of Hainan Medical University
• Subjects: Mycoplasma pneumonia; Transfer factor oral solution; Infection
• Online Access: http://www.hnykdxxb.com/PDF/201814/15.pdf

Objective: To explore the effect of adjuvant transfer factor oral solution therapy on the infection process of children with mycoplasma pneumonia. Methods: A total of 164 children with mycoplasma pneumonia who were treated in our hospital between January 2017 and January 2018 were selected as the research subjects and divided into control group (n=82) and transfer factor oral solution group (n=82) by random number table method. Control group received clinical routine therapy for children with mycoplasma pneumonia, transfer factor oral solution group received both routine therapy and transfer factor oral solution therapy, and both groups were treated for consecutive 1 week. The differences in infection-related index levels were compared between the two groups before and after treatment. Results: Before treatment, the differences in serum levels of inflammatory factors, coagulation indexes and immunoglobulins were not statistically significant between the two groups. After 1 week of treatment, serum inflammatory factors IL-2, IL-13 and IL-18 contents of transfer factor oral solution group were lower than those of control group; serum coagulation index FIB level was lower than that of control group whereas PT and APTT levels were higher than those of control group; serum immunoglobulins IgG, IgA and IgM contents were lower than those of control group. Conclusion: Adjuvant transfer factor oral solution therapy can effectively relieve the systemic inflammatory response and reduce the coagulation system and humoral immune system function damage in children with mycoplasma pneumonia.