The Involvement of Aβ42 and Tau in Nucleolar and Protein Synthesis Machinery Dysfunction
Alzheimer’s disease (AD) is the most common form of dementia and is distinguished from other dementias by observation of extracellular Amyloid-β (Aβ) plaques and intracellular neurofibrillary tangles, comprised of fibrils of Aβ and tau protein, respectively. At early stages, AD is characterized by m...
Main Authors: | Mahmoud B. Maina, Laura J. Bailey, Aidan J. Doherty, Louise C. Serpell |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2018-08-01
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Series: | Frontiers in Cellular Neuroscience |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fncel.2018.00220/full |
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