Intrathoracic Endotracheal Metastasis from Nasopharyngeal Carcinoma:A First Case Report and Review of the Literature
Intrathoracic endotracheal metastasis from a very distant site is extremely rare. We report the first case of such a disease in a 68-year-old man with nasopharyngeal carcinoma who presented with a cough and hemoptysis 34 months after finishing radiotherapy. Prior to tracheal metastasis, he developed...
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doaj-90242ec4af8c4946aff8ec43a347d3f92020-11-25T00:12:45ZengKarger PublishersCase Reports in Oncology1662-65752010-05-013216016410.1159/000314233314233Intrathoracic Endotracheal Metastasis from Nasopharyngeal Carcinoma:A First Case Report and Review of the LiteratureHeming LuJiaxin ChenYanyan XieJinjian ChengYanrong HaoLuxing PengQiang PangShan DengJunzhao GuJian QinZhiping LuIntrathoracic endotracheal metastasis from a very distant site is extremely rare. We report the first case of such a disease in a 68-year-old man with nasopharyngeal carcinoma who presented with a cough and hemoptysis 34 months after finishing radiotherapy. Prior to tracheal metastasis, he developed a solitary metastasis in the lung and underwent chemotherapy followed by radiotherapy. Computed tomography showed the presence of an enlarged lymph node in the para-aortic arch. Fiberoptic bronchoscopy revealed an endotracheal tumor 1 cm above the carina. Histological and immunohistochemical analyses confirmed its nasopharyngeal origin. He was treated with conventional radiotherapy and three-dimensional conformal radiotherapy; complete tumor remission was achieved. He died of nonmalignant disease with no signs of tumor recurrence 2 years after treatment completion. Radiotherapy may be an appropriate management approach to achieve long-term tumor control for this disease.http://www.karger.com/Article/FullText/314233RadiotherapyMetastatic diseaseEndotracheal malignancyNasopharyngeal carcinoma |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Heming Lu Jiaxin Chen Yanyan Xie Jinjian Cheng Yanrong Hao Luxing Peng Qiang Pang Shan Deng Junzhao Gu Jian Qin Zhiping Lu |
spellingShingle |
Heming Lu Jiaxin Chen Yanyan Xie Jinjian Cheng Yanrong Hao Luxing Peng Qiang Pang Shan Deng Junzhao Gu Jian Qin Zhiping Lu Intrathoracic Endotracheal Metastasis from Nasopharyngeal Carcinoma:A First Case Report and Review of the Literature Case Reports in Oncology Radiotherapy Metastatic disease Endotracheal malignancy Nasopharyngeal carcinoma |
author_facet |
Heming Lu Jiaxin Chen Yanyan Xie Jinjian Cheng Yanrong Hao Luxing Peng Qiang Pang Shan Deng Junzhao Gu Jian Qin Zhiping Lu |
author_sort |
Heming Lu |
title |
Intrathoracic Endotracheal Metastasis from Nasopharyngeal Carcinoma:A First Case Report and Review of the Literature |
title_short |
Intrathoracic Endotracheal Metastasis from Nasopharyngeal Carcinoma:A First Case Report and Review of the Literature |
title_full |
Intrathoracic Endotracheal Metastasis from Nasopharyngeal Carcinoma:A First Case Report and Review of the Literature |
title_fullStr |
Intrathoracic Endotracheal Metastasis from Nasopharyngeal Carcinoma:A First Case Report and Review of the Literature |
title_full_unstemmed |
Intrathoracic Endotracheal Metastasis from Nasopharyngeal Carcinoma:A First Case Report and Review of the Literature |
title_sort |
intrathoracic endotracheal metastasis from nasopharyngeal carcinoma:a first case report and review of the literature |
publisher |
Karger Publishers |
series |
Case Reports in Oncology |
issn |
1662-6575 |
publishDate |
2010-05-01 |
description |
Intrathoracic endotracheal metastasis from a very distant site is extremely rare. We report the first case of such a disease in a 68-year-old man with nasopharyngeal carcinoma who presented with a cough and hemoptysis 34 months after finishing radiotherapy. Prior to tracheal metastasis, he developed a solitary metastasis in the lung and underwent chemotherapy followed by radiotherapy. Computed tomography showed the presence of an enlarged lymph node in the para-aortic arch. Fiberoptic bronchoscopy revealed an endotracheal tumor 1 cm above the carina. Histological and immunohistochemical analyses confirmed its nasopharyngeal origin. He was treated with conventional radiotherapy and three-dimensional conformal radiotherapy; complete tumor remission was achieved. He died of nonmalignant disease with no signs of tumor recurrence 2 years after treatment completion. Radiotherapy may be an appropriate management approach to achieve long-term tumor control for this disease. |
topic |
Radiotherapy Metastatic disease Endotracheal malignancy Nasopharyngeal carcinoma |
url |
http://www.karger.com/Article/FullText/314233 |
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