A Analytical Review on Methods for the Isolation and Determination of Glycyrrhizic Acid from Glycyrrhiza glabra

Glycyrrhiza glabra (Licorice) is a perennial shrub belongs to the Fabaceae family. It is widely used in food pharmaceutical products and tobacco industry because of its important secondary metabolites. Due to worldwide uses of licorice, it has significant role in export. One of the main bioactive co...

Full description

Bibliographic Details
Main Authors: M Khanahmadi, H Naghdi Badi, S Akhondzadeh, F Khalighi–Sigaroodi, A Mehrafarin, S Shahriari, R Hajiaghaee
Format: Article
Language:English
Published: Institue of Medicinal Plants, ACECR 2014-05-01
Series:Journal of Medicinal Plants
Subjects:
Online Access:http://jmp.ir/article-1-27-en.html
id doaj-902b303b4e534a8ab308264576f01a21
record_format Article
spelling doaj-902b303b4e534a8ab308264576f01a212021-09-19T04:22:59ZengInstitue of Medicinal Plants, ACECRJournal of Medicinal Plants2717-204X2717-20582014-05-011350110A Analytical Review on Methods for the Isolation and Determination of Glycyrrhizic Acid from Glycyrrhiza glabraM Khanahmadi0H Naghdi Badi1S Akhondzadeh2F Khalighi–Sigaroodi3A Mehrafarin4S Shahriari5R Hajiaghaee6 ACECR, Kermanshah Branch Medicinal Plants Research Center, Institute of Medicinal Plants, ACECR Tehran University of Medical Sciences Medicinal Plants Research Center, Institute of Medicinal Plants, ACECR Medicinal Plants Research Center, Institute of Medicinal Plants, ACECR ACECR, Kermanshah Branch Medicinal Plants Research Center, Institute of Medicinal Plants, ACECR Glycyrrhiza glabra (Licorice) is a perennial shrub belongs to the Fabaceae family. It is widely used in food pharmaceutical products and tobacco industry because of its important secondary metabolites. Due to worldwide uses of licorice, it has significant role in export. One of the main bioactive compounds of the root is glycyrrhizic acid (GA) which is a saponine containing three carboxyl and five hydroxyl groups. Glycyrrhizic acid is used as an anti-inflammatory and anti-allergic remedy for the treatment of bronchial asthma, eczemas and other diseases. There are different methods for separation, purification, and analysis of glycyrrhizic acid (GA) from licorice roots. Most accepted technologies of them include using of solvents, water separation, polymeric macro porous resin and non-ionic surfactants. Also, high-performance liquid chromatography technique is the most important in analysis of GA.http://jmp.ir/article-1-27-en.htmlglycyrrhiza glabraglycyrrhizinglycyrrhizic acidglycyrrhetinic acidpurification and separation
collection DOAJ
language English
format Article
sources DOAJ
author M Khanahmadi
H Naghdi Badi
S Akhondzadeh
F Khalighi–Sigaroodi
A Mehrafarin
S Shahriari
R Hajiaghaee
spellingShingle M Khanahmadi
H Naghdi Badi
S Akhondzadeh
F Khalighi–Sigaroodi
A Mehrafarin
S Shahriari
R Hajiaghaee
A Analytical Review on Methods for the Isolation and Determination of Glycyrrhizic Acid from Glycyrrhiza glabra
Journal of Medicinal Plants
glycyrrhiza glabra
glycyrrhizin
glycyrrhizic acid
glycyrrhetinic acid
purification and separation
author_facet M Khanahmadi
H Naghdi Badi
S Akhondzadeh
F Khalighi–Sigaroodi
A Mehrafarin
S Shahriari
R Hajiaghaee
author_sort M Khanahmadi
title A Analytical Review on Methods for the Isolation and Determination of Glycyrrhizic Acid from Glycyrrhiza glabra
title_short A Analytical Review on Methods for the Isolation and Determination of Glycyrrhizic Acid from Glycyrrhiza glabra
title_full A Analytical Review on Methods for the Isolation and Determination of Glycyrrhizic Acid from Glycyrrhiza glabra
title_fullStr A Analytical Review on Methods for the Isolation and Determination of Glycyrrhizic Acid from Glycyrrhiza glabra
title_full_unstemmed A Analytical Review on Methods for the Isolation and Determination of Glycyrrhizic Acid from Glycyrrhiza glabra
title_sort analytical review on methods for the isolation and determination of glycyrrhizic acid from glycyrrhiza glabra
publisher Institue of Medicinal Plants, ACECR
series Journal of Medicinal Plants
issn 2717-204X
2717-2058
publishDate 2014-05-01
description Glycyrrhiza glabra (Licorice) is a perennial shrub belongs to the Fabaceae family. It is widely used in food pharmaceutical products and tobacco industry because of its important secondary metabolites. Due to worldwide uses of licorice, it has significant role in export. One of the main bioactive compounds of the root is glycyrrhizic acid (GA) which is a saponine containing three carboxyl and five hydroxyl groups. Glycyrrhizic acid is used as an anti-inflammatory and anti-allergic remedy for the treatment of bronchial asthma, eczemas and other diseases. There are different methods for separation, purification, and analysis of glycyrrhizic acid (GA) from licorice roots. Most accepted technologies of them include using of solvents, water separation, polymeric macro porous resin and non-ionic surfactants. Also, high-performance liquid chromatography technique is the most important in analysis of GA.
topic glycyrrhiza glabra
glycyrrhizin
glycyrrhizic acid
glycyrrhetinic acid
purification and separation
url http://jmp.ir/article-1-27-en.html
work_keys_str_mv AT mkhanahmadi aanalyticalreviewonmethodsfortheisolationanddeterminationofglycyrrhizicacidfromglycyrrhizaglabra
AT hnaghdibadi aanalyticalreviewonmethodsfortheisolationanddeterminationofglycyrrhizicacidfromglycyrrhizaglabra
AT sakhondzadeh aanalyticalreviewonmethodsfortheisolationanddeterminationofglycyrrhizicacidfromglycyrrhizaglabra
AT fkhalighisigaroodi aanalyticalreviewonmethodsfortheisolationanddeterminationofglycyrrhizicacidfromglycyrrhizaglabra
AT amehrafarin aanalyticalreviewonmethodsfortheisolationanddeterminationofglycyrrhizicacidfromglycyrrhizaglabra
AT sshahriari aanalyticalreviewonmethodsfortheisolationanddeterminationofglycyrrhizicacidfromglycyrrhizaglabra
AT rhajiaghaee aanalyticalreviewonmethodsfortheisolationanddeterminationofglycyrrhizicacidfromglycyrrhizaglabra
AT mkhanahmadi analyticalreviewonmethodsfortheisolationanddeterminationofglycyrrhizicacidfromglycyrrhizaglabra
AT hnaghdibadi analyticalreviewonmethodsfortheisolationanddeterminationofglycyrrhizicacidfromglycyrrhizaglabra
AT sakhondzadeh analyticalreviewonmethodsfortheisolationanddeterminationofglycyrrhizicacidfromglycyrrhizaglabra
AT fkhalighisigaroodi analyticalreviewonmethodsfortheisolationanddeterminationofglycyrrhizicacidfromglycyrrhizaglabra
AT amehrafarin analyticalreviewonmethodsfortheisolationanddeterminationofglycyrrhizicacidfromglycyrrhizaglabra
AT sshahriari analyticalreviewonmethodsfortheisolationanddeterminationofglycyrrhizicacidfromglycyrrhizaglabra
AT rhajiaghaee analyticalreviewonmethodsfortheisolationanddeterminationofglycyrrhizicacidfromglycyrrhizaglabra
_version_ 1717376659303170048