Pre-opereative Parathormone Levels are Correlated with Mean Diameter of Parathyroid Adenoma and Pre-operative Serum Calcium and Alkaline Phosphatase Levels
The aim of the present study was to determine the relationship between biochemical parameters, mean diameter of parathyroid adenoma (MDPA) and parathyroid hormone (PTH) levels in patients who underwent parathyroid surgery.Materials and Methods: Data were collected retrospectively from patients with...
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doaj-9047769e285f45168e4810b6112e98972020-11-25T00:01:35ZengSociety of TURAZ AKADEMI Medicine Science2147-06342015-09-014324011310.5455/medscience.2015.04.8257172492Pre-opereative Parathormone Levels are Correlated with Mean Diameter of Parathyroid Adenoma and Pre-operative Serum Calcium and Alkaline Phosphatase LevelsGulsah Elbuken0Recep Aktimur1Kadir Yildirim2Sude Hatun Aktimur3Mehmet Derya Demirag4Aysu Basak Ozbalci5Mustafa Bakirtas6Banu KirtilogluNuraydin OzlemSamsun Training and Research Hospital, Department of Endocrinology and Metabolism, Samsun, Turkey Samsun Training and Research Hospital, Department of General Surgery, Samsun, Turkey Samsun Training and Research Hospital, Department of General Surgery Samsun, Turkey Samsun Training and Research Hospital, Department of Internal Medicine, Samsun, Turkey Samsun Training and Research Hospital, Department of Internal Medicine, Samsun, Turkey Samsun Training and Research Hospital, Department of Radiology, Samsun, Turkey Samsun Training and Research Hospital, Department of Pathology, Samsun, Turkey Samsun Training and Research Hospital, Department of Nuclear Medicine, Samsun, Turkey Samsun Training and Research Hospital, Department of General Surgery, Samsun, TurkeyThe aim of the present study was to determine the relationship between biochemical parameters, mean diameter of parathyroid adenoma (MDPA) and parathyroid hormone (PTH) levels in patients who underwent parathyroid surgery.Materials and Methods: Data were collected retrospectively from patients with hyperparathyroidism who were operated and followed in our hospital between September 2011 and April 2014. Twenty-nine (male/female = 8/21) patients with a mean age of 58.31 ± 12.59 years were enrolled into the study. The mean pre-operative serum calcium and intact PTH (iPTH) levels were 11.98±1.23 mg/dl and 386.52±374.96 pg/ml, respectively. Serum pre-operative calcium levels were found to be significantly higher in patients who had nephrolithiasis than those who did not, whereas pre-operative serum phosphate levels were lower. Pre-operative iPTH levels were found to be correlated with pre-operative calcium, alkaline phosphatase and MDPA but not with pre-operative serum phosphate. Also, pre-operative calcium levels were found to be significantly correlated with MDPA.Conclusion: Presence of nephrolithiasis is associated with higher pre-operative calcium and lower phosphate levels. Pre-operative iPTH and calcium levels were also found to be significantly correlated with MDPA; this suggests that serum iPTH and calcium levels can be useful in predicting MDPA. [Med-Science 2015; 4(3.000): 2401-13]http://www.ejmanager.com/fulltextpdf.php?mno=172492Hypercalcemiaprimary hyperparathyroidismparathyroid adenomaparathormonecalcium |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Gulsah Elbuken Recep Aktimur Kadir Yildirim Sude Hatun Aktimur Mehmet Derya Demirag Aysu Basak Ozbalci Mustafa Bakirtas Banu Kirtiloglu Nuraydin Ozlem |
spellingShingle |
Gulsah Elbuken Recep Aktimur Kadir Yildirim Sude Hatun Aktimur Mehmet Derya Demirag Aysu Basak Ozbalci Mustafa Bakirtas Banu Kirtiloglu Nuraydin Ozlem Pre-opereative Parathormone Levels are Correlated with Mean Diameter of Parathyroid Adenoma and Pre-operative Serum Calcium and Alkaline Phosphatase Levels Medicine Science Hypercalcemia primary hyperparathyroidism parathyroid adenoma parathormone calcium |
author_facet |
Gulsah Elbuken Recep Aktimur Kadir Yildirim Sude Hatun Aktimur Mehmet Derya Demirag Aysu Basak Ozbalci Mustafa Bakirtas Banu Kirtiloglu Nuraydin Ozlem |
author_sort |
Gulsah Elbuken |
title |
Pre-opereative Parathormone Levels are Correlated with Mean Diameter of Parathyroid Adenoma and Pre-operative Serum Calcium and Alkaline Phosphatase Levels |
title_short |
Pre-opereative Parathormone Levels are Correlated with Mean Diameter of Parathyroid Adenoma and Pre-operative Serum Calcium and Alkaline Phosphatase Levels |
title_full |
Pre-opereative Parathormone Levels are Correlated with Mean Diameter of Parathyroid Adenoma and Pre-operative Serum Calcium and Alkaline Phosphatase Levels |
title_fullStr |
Pre-opereative Parathormone Levels are Correlated with Mean Diameter of Parathyroid Adenoma and Pre-operative Serum Calcium and Alkaline Phosphatase Levels |
title_full_unstemmed |
Pre-opereative Parathormone Levels are Correlated with Mean Diameter of Parathyroid Adenoma and Pre-operative Serum Calcium and Alkaline Phosphatase Levels |
title_sort |
pre-opereative parathormone levels are correlated with mean diameter of parathyroid adenoma and pre-operative serum calcium and alkaline phosphatase levels |
publisher |
Society of TURAZ AKADEMI |
series |
Medicine Science |
issn |
2147-0634 |
publishDate |
2015-09-01 |
description |
The aim of the present study was to determine the relationship between biochemical parameters, mean diameter of parathyroid adenoma (MDPA) and parathyroid hormone (PTH) levels in patients who underwent parathyroid surgery.Materials and Methods: Data were collected retrospectively from patients with hyperparathyroidism who were operated and followed in our hospital between September 2011 and April 2014. Twenty-nine (male/female = 8/21) patients with a mean age of 58.31 ± 12.59 years were enrolled into the study. The mean pre-operative serum calcium and intact PTH (iPTH) levels were 11.98±1.23 mg/dl and 386.52±374.96 pg/ml, respectively. Serum pre-operative calcium levels were found to be significantly higher in patients who had nephrolithiasis than those who did not, whereas pre-operative serum phosphate levels were lower. Pre-operative iPTH levels were found to be correlated with pre-operative calcium, alkaline phosphatase and MDPA but not with pre-operative serum phosphate. Also, pre-operative calcium levels were found to be significantly correlated with MDPA.Conclusion: Presence of nephrolithiasis is associated with higher pre-operative calcium and lower phosphate levels. Pre-operative iPTH and calcium levels were also found to be significantly correlated with MDPA; this suggests that serum iPTH and calcium levels can be useful in predicting MDPA. [Med-Science 2015; 4(3.000): 2401-13] |
topic |
Hypercalcemia primary hyperparathyroidism parathyroid adenoma parathormone calcium |
url |
http://www.ejmanager.com/fulltextpdf.php?mno=172492 |
work_keys_str_mv |
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