The ubiquitin E3 ligase NOSIP modulates protein phosphatase 2A activity in craniofacial development.
Holoprosencephaly is a common developmental disorder in humans characterised by incomplete brain hemisphere separation and midface anomalies. The etiology of holoprosencephaly is heterogeneous with environmental and genetic causes, but for a majority of holoprosencephaly cases the genes associated w...
Main Authors: | Meike Hoffmeister, Carola Prelle, Philipp Küchler, Igor Kovacevic, Markus Moser, Werner Müller-Esterl, Stefanie Oess |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4278855?pdf=render |
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