Increased Expression of a MicroRNA Correlates with Anthelmintic Resistance in Parasitic Nematodes

Increased Expression of a MicroRNA Correlates with Anthelmintic Resistance in Parasitic Nematodes

Resistance to anthelmintic drugs is a major problem in the global fight against parasitic nematodes infecting humans and animals. While previous studies have identified mutations in drug target genes in resistant parasites, changes in the expression levels of both targets and transporters have also...

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Bibliographic Details
Main Authors: Victoria Gillan, Kirsty Maitland, Roz Laing, Henry Gu, Neil D. Marks, Alan D. Winter, David Bartley, Alison Morrison, Philip J. Skuce, Andrew M. Rezansoff, John S. Gilleard, Axel Martinelli, Collette Britton, Eileen Devaney
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
parasitic nematode
Haemonchus
drug resistance
microRNA
ivermectin
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2017.00452/full

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