Synthesis and Characterization of a New Bivalent Ligand Combining Caffeine and Docosahexaenoic Acid

Synthesis and Characterization of a New Bivalent Ligand Combining Caffeine and Docosahexaenoic Acid

Caffeine is a promising drug for the management of neurodegenerative diseases such as Parkinson’s disease (PD), demonstrating neuroprotective properties that have been attributed to its interaction with the basal ganglia adenosine A2A receptor (A2AR). However, the doses needed to exert these neuropr...

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Bibliographic Details
Main Authors:	Víctor Fernández-Dueñas, Jhonny Azuaje, Xavier Morató, Begoña Cordobilla, Joan Carles Domingo, Eddy Sotelo, Francisco Ciruela
Format:	Article
Language:	English
Published:	MDPI AG 2017-02-01
Series:	Molecules
Subjects:	adenosine A2A receptor caffeine docosahexaenoic acid (DHA) inverse agonism
Online Access:	http://www.mdpi.com/1420-3049/22/3/366

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