STAT5 and CD4+ T Cell Immunity [version 1; referees: 4 approved]

STAT5 and CD4+ T Cell Immunity [version 1; referees: 4 approved]

STAT5 plays a critical role in the development and function of many cell types. Here, we review the role of STAT5 in the development of T lymphocytes in the thymus and its subsequent role in the differentiation of distinct CD4+ helper and regulatory T-cell subsets.

Bibliographic Details
Main Authors: David L. Owen, Michael A. Farrar
Format: Article
Language:English
Published: F1000 Research Ltd 2017-01-01
Series:F1000Research
Subjects:
Autoimmunity
Innate Immunity
Leukocyte Development
Leukocyte Signaling & Gene Expression
Online Access:https://f1000research.com/articles/6-32/v1
Description
Summary:STAT5 plays a critical role in the development and function of many cell types. Here, we review the role of STAT5 in the development of T lymphocytes in the thymus and its subsequent role in the differentiation of distinct CD4+ helper and regulatory T-cell subsets.
ISSN:2046-1402

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